Concentration, motility and morphology are parameters commonly used to determine the
fertilization potential of an ejaculate. These parameters give a general view on the quality of …

The functional significance of deoxyribonucleic acid (DNA) fragmentation in ejaculated
human sperm is unclear. In this study the extent of DNA strand breakage in swim‐up …

OBJECTIVE: To review the mechanisms responsible for DNA fragmentation in human
sperm, including those occurring during spermatogenesis and transport through the …

Sperm DNA Fragmentation has been extensively studied for more than a decade. In the
1940s the uniqueness of the spermatozoa protein complex which stabilizes the DNA was …

Spermatozoa have the task to deliver an intact paternal genome to the oocyte and to support
a successful embryo development. The high levels of sperm DNA fragmentation (sDF) found …

Despite the ever-increasing knowledge of the fertilization process, there is still a need for
better understanding of the causes of sperm DNA fragmentation and its impact on …

Reproductive diseases have become a growing worldwide problem and male factor plays
an important role in the reproductive diagnosis, prognosis and design of assisted …

Numerous studies have shown the presence of DNA strand breaks in human ejaculated
spermatozoa. The nature of this nuclear anomaly and its relationship to patient etiology is …

Sperm DNA fragmentation (sDF) represents a threat to male fertility, human reproduction
and the health of the offspring. The causes of sDF are still unclear, even if apoptosis …

Sperm DNA fragmentation is referred to as one of the main causes of male infertility. Failures
in the protamination process, apoptosis and action of reactive oxygen species (ROS) are …