Culturable endophytes of medicinal plants and the genetic basis for their bioactivity

KI Miller, C Qing, DMY Sze, BD Roufogalis, BA Neilan - Microbial Ecology, 2012 - Springer
The bioactive compounds of medicinal plants are products of the plant itself or of
endophytes living inside the plant. Endophytes isolated from eight different anticancer plants …

Investigation of the biosynthetic potential of endophytes in traditional Chinese anticancer herbs

KI Miller, C Qing, DMY Sze, BA Neilan - PLoS One, 2012 - journals.plos.org
Traditional Chinese medicine encompasses a rich empirical knowledge of the use of plants
for the treatment of disease. In addition, the microorganisms associated with medicinal …

Unlocking the potential of bacterial endophytes from medicinal plants for drug discovery

SB Zotchev - Microbial Biotechnology, 2024 - Wiley Online Library
Among the plant‐associated microorganisms, the so‐called endophytes continue to attract
much attention because of their ability not only to protect host plants from biotic and abiotic …

The diversity and anti-microbial activity of endophytic actinomycetes isolated from medicinal plants in Panxi plateau, China

K Zhao, P Penttinen, T Guan, J Xiao, Q Chen, J Xu… - Current …, 2011 - Springer
Traditional Chinese medicinal plants are sources of biologically active compounds,
providing raw material for pharmaceutical, cosmetic and fragrance industries. The …

Bioactive endophytes warrant intensified exploration and conservation

SA Smith, DC Tank, LA Boulanger, CA Bascom-Slack… - PLoS …, 2008 - journals.plos.org
Background A key argument in favor of conserving biodiversity is that as yet undiscovered
biodiversity will yield products of great use to humans. However, the link between …

The diversity of anti-microbial secondary metabolites produced by fungal endophytes: an interdisciplinary perspective

WK Mousa, MN Raizada - Frontiers in microbiology, 2013 - frontiersin.org
Endophytes are microbes that inhabit host plants without causing disease and are reported
to be reservoirs of metabolites that combat microbes and other pathogens. Here we review …

Cultivable endophyte resources in medicinal plants and effects on hosts

Y Wang, Y Zhang, H Cong, C Li, J Wu, L Li, J Jiang… - Life, 2023 - mdpi.com
With the increasing demand for medicinal plants and the increasing shortage of resources,
improving the quality and yield of medicinal plants and making more effective use of …

Secondary metabolites from endophytic fungi: chemical diversity and application

H Meena, S Hnamte, B Siddhardha - Advances in endophytic fungal …, 2019 - Springer
Two major challenges facing the world today are antibiotic resistance, an emerging threat to
human health, and, in agriculture, deterioration in crop yields due to pathogenic …

[PDF][PDF] Bioactive natural products from endophytic microbes

H Zhang, X Bai, M Zhang, J Chen… - The Natural Products …, 2018 - researchgate.net
A growing body of evidence has indicated that endophytic microorganism is one of the
important prolific producers of natural products with potential application in new drug …

Plants as the extended phenotype of endophytes—the actual source of bioactive compounds

N Rutkowska, P Drożdżyński, M Ryngajłło… - International Journal of …, 2023 - mdpi.com
For thousands of years, plants have been used for their medicinal properties. The industrial
production of plant-beneficial compounds is facing many drawbacks, such as seasonal …