The continuing increase in the prevalence of obesity and metabolic disorders such as type‐II
diabetes and an accelerating aging population globally will remain the major contributors to …

The mammalian target of rapamycin (mTOR), an evolutionarily conserved serine/threonine
kinase, plays a significant role in integrating cellular and environmental cues that modulate …

The mTOR (mechanistic target of rapamycin) is a master regulator of several crucial cellular
processes, including protein synthesis, cellular growth, proliferation, autophagy, lysosomal …

Aging is a physiologic/pathologic process characterized by a progressive impairment of
cellular functions, supported by the alterations of several molecular pathways, leading to an …

The role of mTOR in lipid homeostasis and diabetes progressi... : Current Opinion in
Endocrinology, Diabetes and Obesity The role of mTOR in lipid homeostasis and diabetes …

The prevalence of obesity and associated medical disorders has increased dramatically in
the United States and throughout much of the world in the past decade. Obesity, induced by …

The complex relationship between diet and metabolism is an important contributor to cellular
metabolism and health. Over the past few decades, a central role for mammalian target of …

The mechanistic target of rapamycin (mTOR) kinase is a central regulator of cell growth and
metabolism. It is the catalytic subunit of two distinct large protein complexes, mTOR complex …

The mTOR pathway integrates a diverse set of environmental cues, such as growth factor
signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half …

The protein kinase mechanistic target of rapamycin (mTOR) functions as a central regulator
of metabolism, integrating diverse nutritional and hormonal cues to control anabolic …