Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma

EN Vithana, CC Khor, C Qiao, ME Nongpiur… - Nature …, 2012 - nature.com
Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We
conducted a genome-wide association study including 1,854 PACG cases and 9,608 …

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

CC Khor, T Do, H Jia, M Nakano, R George… - Nature …, 2016 - nature.com
Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We
conducted a genome-wide association study (GWAS) followed by replication in a combined …

[HTML][HTML] The genetic mechanisms of primary angle closure glaucoma

DF Ahram, WL Alward, MH Kuehn - Eye, 2015 - nature.com
Abstract Primary Angle Closure Glaucoma (PACG) is one of the most common types of
glaucoma affecting over 15 million individuals worldwide. Family history and ethnicity are …

[HTML][HTML] ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma

ME Nongpiur, CC Khor, H Jia, BK Cornes… - PLoS …, 2014 - journals.plos.org
Anterior chamber depth (ACD) is a key anatomical risk factor for primary angle closure
glaucoma (PACG). We conducted a genome-wide association study (GWAS) on ACD to …

Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma

G Thorleifsson, GB Walters, AW Hewitt, G Masson… - Nature …, 2010 - nature.com
We conducted a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a …

Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma

Y Shiga, M Akiyama, KM Nishiguchi… - Human molecular …, 2018 - academic.oup.com
Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness
worldwide for which 15 disease-associated loci had been discovered. Among them, only 5 …

Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma

Y Chen, Y Lin, EN Vithana, L Jia, X Zuo, TY Wong… - Nature …, 2014 - nature.com
We performed a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,007 cases with high-pressure glaucoma (HPG) and 1,009 controls from southern China …

Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1

KP Burdon, S Macgregor, AW Hewitt, S Sharma… - Nature …, 2011 - nature.com
We report a genome-wide association study for open-angle glaucoma (OAG) blindness
using a discovery cohort of 590 individuals with severe visual field loss (cases) and 3,956 …

[HTML][HTML] Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations

PWM Bonnemaijer, AI Iglesias, GN Nadkarni… - Human genetics, 2018 - Springer
Primary open angle glaucoma (POAG) is a complex disease with a major genetic
contribution. Its prevalence varies greatly among ethnic groups, and is up to five times more …

[HTML][HTML] Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry

Y Liu, MA Hauser, SK Akafo, X Qin… - … & visual science, 2013 - tvst.arvojournals.org
Purpose.: Multiple genes have been associated with primary open angle glaucoma (POAG)
in Caucasian populations. We now examine the association of these loci in populations of …