Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma
Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We
conducted a genome-wide association study including 1,854 PACG cases and 9,608 …
conducted a genome-wide association study including 1,854 PACG cases and 9,608 …
Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma
Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We
conducted a genome-wide association study (GWAS) followed by replication in a combined …
conducted a genome-wide association study (GWAS) followed by replication in a combined …
[HTML][HTML] The genetic mechanisms of primary angle closure glaucoma
Abstract Primary Angle Closure Glaucoma (PACG) is one of the most common types of
glaucoma affecting over 15 million individuals worldwide. Family history and ethnicity are …
glaucoma affecting over 15 million individuals worldwide. Family history and ethnicity are …
[HTML][HTML] ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma
Anterior chamber depth (ACD) is a key anatomical risk factor for primary angle closure
glaucoma (PACG). We conducted a genome-wide association study (GWAS) on ACD to …
glaucoma (PACG). We conducted a genome-wide association study (GWAS) on ACD to …
Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma
We conducted a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a …
in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a …
Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma
Y Shiga, M Akiyama, KM Nishiguchi… - Human molecular …, 2018 - academic.oup.com
Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness
worldwide for which 15 disease-associated loci had been discovered. Among them, only 5 …
worldwide for which 15 disease-associated loci had been discovered. Among them, only 5 …
Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma
We performed a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,007 cases with high-pressure glaucoma (HPG) and 1,009 controls from southern China …
in 1,007 cases with high-pressure glaucoma (HPG) and 1,009 controls from southern China …
Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1
We report a genome-wide association study for open-angle glaucoma (OAG) blindness
using a discovery cohort of 590 individuals with severe visual field loss (cases) and 3,956 …
using a discovery cohort of 590 individuals with severe visual field loss (cases) and 3,956 …
[HTML][HTML] Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations
PWM Bonnemaijer, AI Iglesias, GN Nadkarni… - Human genetics, 2018 - Springer
Primary open angle glaucoma (POAG) is a complex disease with a major genetic
contribution. Its prevalence varies greatly among ethnic groups, and is up to five times more …
contribution. Its prevalence varies greatly among ethnic groups, and is up to five times more …
[HTML][HTML] Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry
Purpose.: Multiple genes have been associated with primary open angle glaucoma (POAG)
in Caucasian populations. We now examine the association of these loci in populations of …
in Caucasian populations. We now examine the association of these loci in populations of …