Silencing of foreign DNA in bacteria
Xenogeneic silencing proteins facilitate horizontal gene transfer by silencing expression of
AT-rich sequences. By virtue of their activity these proteins serve as master regulators of a …
AT-rich sequences. By virtue of their activity these proteins serve as master regulators of a …
Xenogeneic silencing and bacterial genome evolution: mechanisms for DNA recognition imply multifaceted roles of xenogeneic silencers
Horizontal gene transfer (HGT) is a major driving force for bacterial evolution. To avoid the
deleterious effects due to the unregulated expression of newly acquired foreign genes …
deleterious effects due to the unregulated expression of newly acquired foreign genes …
[HTML][HTML] A novel AT-rich DNA recognition mechanism for bacterial xenogeneic silencer MvaT
P Ding, KA McFarland, S Jin, G Tong, B Duan… - PLoS …, 2015 - journals.plos.org
Bacterial xenogeneic silencing proteins selectively bind to and silence expression from
many AT rich regions of the chromosome. They serve as master regulators of horizontally …
many AT rich regions of the chromosome. They serve as master regulators of horizontally …
Structural basis for recognition of AT-rich DNA by unrelated xenogeneic silencing proteins
BRG Gordon, Y Li, A Cote… - Proceedings of the …, 2011 - National Acad Sciences
H-NS and Lsr2 are nucleoid-associated proteins from Gram-negative bacteria and
Mycobacteria, respectively, that play an important role in the silencing of horizontally …
Mycobacteria, respectively, that play an important role in the silencing of horizontally …
The impact of gene silencing on horizontal gene transfer and bacterial evolution
WW Navarre - Advances in microbial physiology, 2016 - Elsevier
The H-NS family of DNA-binding proteins is the subject of intense study due to its important
roles in the regulation of horizontally acquired genes critical for virulence, antibiotic …
roles in the regulation of horizontally acquired genes critical for virulence, antibiotic …
[HTML][HTML] Xenogeneic silencing strategies in bacteria are dictated by RNA polymerase promiscuity
Horizontal gene transfer facilitates dissemination of favourable traits among bacteria.
However, foreign DNA can also reduce host fitness: incoming sequences with a higher AT …
However, foreign DNA can also reduce host fitness: incoming sequences with a higher AT …
Anti-silencing: overcoming H-NS-mediated repression of transcription in Gram-negative enteric bacteria
DM Stoebel, A Free, CJ Dorman - Microbiology, 2008 - microbiologyresearch.org
The H-NS nucleoid-associated DNA-binding protein is an important global repressor of
transcription in Gram-negative bacteria. Recently, H-NS has been implicated in the process …
transcription in Gram-negative bacteria. Recently, H-NS has been implicated in the process …
Degradation of gene silencer is essential for expression of foreign genes and bacterial colonization of the mammalian gut
J Choi, M Schmukler… - Proceedings of the …, 2022 - National Acad Sciences
Horizontal gene transfer drives bacterial evolution. To confer new properties, horizontally
acquired genes must overcome gene silencing by nucleoid-associated proteins, such as the …
acquired genes must overcome gene silencing by nucleoid-associated proteins, such as the …
High‐order oligomerization is required for the function of the H‐NS family member MvaT in Pseudomonas aeruginosa
S Castang, SL Dove - Molecular microbiology, 2010 - Wiley Online Library
H‐NS is an abundant DNA‐binding protein that has been implicated in the silencing of
foreign DNA in several different bacteria. The ability of H‐NS dimers to form higher‐order …
foreign DNA in several different bacteria. The ability of H‐NS dimers to form higher‐order …
How bacterial xenogeneic silencer rok distinguishes foreign from self DNA in its resident genome
Bacterial xenogeneic silencers play important roles in bacterial evolution by recognizing and
inhibiting expression from foreign genes acquired through horizontal gene transfer, thereby …
inhibiting expression from foreign genes acquired through horizontal gene transfer, thereby …