Nicotianamine Functions in the Phloem-Based Transport of Iron to Sink Organs, in Pollen Development and Pollen Tube Growth in Arabidopsis

M Schuler, R Rellán-Álvarez, C Fink-Straube… - The Plant …, 2012 - academic.oup.com
The metal chelator nicotianamine promotes the bioavailability of Fe and reduces cellular Fe
toxicity. For breeding Fe-efficient crops, we need to explore the fundamental impact of …

The analysis of Arabidopsis nicotianamine synthase mutants reveals functions for nicotianamine in seed iron loading and iron deficiency responses

M Klatte, M Schuler, M Wirtz, C Fink-Straube… - Plant …, 2009 - academic.oup.com
Nicotianamine chelates and transports micronutrient metal ions in plants. It has been
speculated that nicotianamine is involved in seed loading with micronutrients. A tomato …

Fe homeostasis in plant cells: does nicotianamine play multiple roles in the regulation of cytoplasmic Fe concentration?

A Pich, R Manteuffel, S Hillmer, G Scholz, W Schmidt - Planta, 2001 - Springer
The cellular and intracellular localization of the non-proteogenic amino acid nicotianamine
(NA) in leaves and root elongation zones was immunochemically investigated in pea (Pisum …

Increased sensitivity to iron deficiency in Arabidopsis thaliana overaccumulating nicotianamine

G Cassin, S Mari, C Curie, JF Briat… - Journal of experimental …, 2009 - academic.oup.com
Nicotianamine (NA) is a non-protein amino acid derivative synthesized from S-adenosyl l-
methionine able to bind several metal ions such as iron, copper, manganese, zinc, or nickel …

Role of nicotianamine in the intracellular delivery of metals and plant reproductive development

M Takahashi, Y Terada, I Nakai, H Nakanishi… - The Plant …, 2003 - academic.oup.com
Nicotianamine (NA), a chelator of metals, is ubiquitously present in higher plants.
Nicotianamine aminotransferase (NAAT) catalyzes the amino group transfer of NA in the …

Nicotianamine: mediator of transport of iron and heavy metals in the phloem?

UW Stephan, G Scholz - Physiologia Plantarum, 1993 - Wiley Online Library
Recent work has demonstrated that minerals in plants are circulated between root and
shoot. This occurs during the whole life time and renders possible response to changing …

Iron-nicotianamine transporters are required for proper long distance iron signaling

RK Kumar, HH Chu, C Abundis, K Vasques… - Plant …, 2017 - academic.oup.com
The mechanisms of root iron uptake and the transcriptional networks that control root-level
regulation of iron uptake have been well studied, but the mechanisms by which shoots …

Vacuolar Nicotianamine Has Critical and Distinct Roles under Iron Deficiency and for Zinc Sequestration in Arabidopsis

MJ Haydon, M Kawachi, M Wirtz, S Hillmer… - The Plant …, 2012 - academic.oup.com
The essential micronutrients Fe and Zn often limit plant growth but are toxic in excess.
Arabidopsis thaliana ZINC-INDUCED FACILITATOR1 (ZIF1) is a vacuolar membrane major …

Map-based cloning of chloronerva, a gene involved in iron uptake of higher plants encoding nicotianamine synthase

HQ Ling, G Koch, H Bäumlein… - Proceedings of the …, 1999 - National Acad Sciences
The uptake of iron in plants is a highly regulated process that is induced on iron starvation.
In tomato, the mutant chloronerva exhibits constitutive expression of iron uptake responses …

Nicotianamine is a major player in plant Zn homeostasis

S Clemens, U Deinlein, H Ahmadi, S Höreth… - Biometals, 2013 - Springer
Nicotianamine (NA) is among the most studied plant metal chelators. A large body of
evidence supports its crucial role for Fe distribution in plants and as a precursor of …