[图书][B] Investigation of novel progression-related methylation events and HOXD genes in prostate cancer
K Kron - 2012 - search.proquest.com
Aberrant DNA methylation in gene promoters causes gene silencing and is a common event
in prostate cancer development and progression. While commonly identified methylated …
in prostate cancer development and progression. While commonly identified methylated …
DNA methylation in promoter region as biomarkers in prostate cancer
M Yang, JY Park - Cancer Epigenetics: Methods and Protocols, 2012 - Springer
The prostate gland is the most common site of cancer and the second leading cause of
cancer death in American men. Recent emerging molecular biological technologies help us …
cancer death in American men. Recent emerging molecular biological technologies help us …
Promoter hypermethylation as a biomarker in prostate adenocarcinoma
JY Park - … risk Assessment, Diagnosis, Treatment, and Prognosis, 2015 - Springer
There is increasing evidence that DNA methylation is a critical source of gene regulation. In
addition, interindividual differences in DNA methylation status in cancer related genes are …
addition, interindividual differences in DNA methylation status in cancer related genes are …
[HTML][HTML] DNA methylation of HOXD3 as a marker of prostate cancer progression
KJ Kron, L Liu, VV Pethe, N Demetrashvili… - Laboratory …, 2010 - Elsevier
DNA methylation in gene promoters causes gene silencing and is a common event in
cancer development and progression. The ability of aberrant methylation events to serve as …
cancer development and progression. The ability of aberrant methylation events to serve as …
Genome-wide DNA methylation profiling identifies novel diagnostic and prognostic biomarkers in early stage prostate cancer.
PHJ Huang, W Göring, T Hielscher, D Weichenhan… - Cancer Research, 2013 - AACR
Prostate cancer (PCa) is the most prevailing cancer in the male population and the second-
leading cause of cancer-related death in the Western world. Although genomic alterations …
leading cause of cancer-related death in the Western world. Although genomic alterations …
Promoter hypermethylation in prostate cancer
JY Park - Cancer Control, 2010 - journals.sagepub.com
Background The prostate gland is the most common site of cancer and the second leading
cause of cancer mortality in American men. It is well known that epigenetic alterations such …
cause of cancer mortality in American men. It is well known that epigenetic alterations such …
Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays
K Kron, V Pethe, L Briollais, B Sadikovic, H Ozcelik… - PloS one, 2009 - journals.plos.org
Background Promoter and 5′ end methylation regulation of tumour suppressor genes is a
common feature of many cancers. Such occurrences often lead to the silencing of these key …
common feature of many cancers. Such occurrences often lead to the silencing of these key …
Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis
Background Despite the significant global loss of DNA hydroxymethylation marks in prostate
cancer tissues, the locus-specific role of hydroxymethylation in prostate tumorigenesis is …
cancer tissues, the locus-specific role of hydroxymethylation in prostate tumorigenesis is …
DNA methylation changes in prostate cancer: current developments and future clinical implementation
MO Hoque - Expert review of molecular diagnostics, 2009 - Taylor & Francis
Promoter hypermethylation is associated with the loss of expression of tumor-suppressor
genes in cancer. Currently, several genome-wide technologies are available and have been …
genes in cancer. Currently, several genome-wide technologies are available and have been …
Identification of novel DNA-methylated genes that correlate with human prostate cancer and high-grade prostatic intraepithelial neoplasia
JM Devaney, S Wang, S Funda, J Long… - Prostate cancer and …, 2013 - nature.com
Background: Prostate cancer (PCa) harbors a myriad of genomic and epigenetic defects.
Cytosine methylation of CpG-rich promoter DNA is an important mechanism of epigenetic …
Cytosine methylation of CpG-rich promoter DNA is an important mechanism of epigenetic …