Microscale thermophoresis (MST) is a new method that enables the quantitative analysis of
molecular interactions in solution at the microliter scale. The technique is based on the …

Interactions between nucleic acids and proteins are driving gene expression programs and
regulating the development of organisms. The binding affinities of transcription factors to …

The study of biomolecular interactions is crucial to get more insight into the biological
system. The interactions of protein-protein, protein-nucleic acids, protein-sugars, nucleic …

Protein-peptide interactions are part of many physiological processes, for example,
epigenetics where peptide regions of histone complexes are crucial for regulation of …

Microscale thermophoresis (MST) allows for quantitative analysis of protein interactions in
free solution and with low sample consumption. The technique is based on thermophoresis …

Microscale thermophoresis (MST) is a biophysical assay to quantify the interaction between
molecules, such as proteins and small molecules. In recent years, the MST assay has been …

Biomolecules, such as RNA, DNA, proteins and polysaccharides, are at the heart of
fundamental cellular processes. These molecules differ greatly with each other in terms of …

Quantitative characterization of protein interactions is essential in practically any field of life
sciences, particularly drug discovery. Most of currently available methods of KD …

The emergence of microscale thermophoresis (MST) as a technique for determining the
dissociation constants for bimolecular interactions has enabled these quantities to be …

The fundamental studies for the binding events of protein and its partner are crucial in drug
development. In this study, a novel technology named microscale thermophoresis (MST) …