Aims Although increased levels of myocardial receptor activator of nuclear factor (NF)-κB
ligand (RANKL) have been reported in heart failure, the role of this pathway in mediating …

Objective: Innate immune response proteins such as inflammatory cytokines, inducible nitric
oxide synthase, and toll like receptors are implicated in myocardial depression and left …

Rationale: Although recent studies have suggested a role for the receptor activator of
nuclear factor κB ligand (RANKL) in the late stages of atherosclerosis (eg, plaque …

The receptor activator of NF-κB ligand (RANKL), a recently identified member of the tumor
necrosis factor (TNF) superfamily, has been shown to induce osteoclastogenesis and …

Objective: We have previously demonstrated that nuclear factor kappa B (NFκB) activation is
needed for the development of cardiac hypertrophy in vivo. NFκB is a downstream …

In the current report, we investigated the possibility of a cross-talk between receptor activator
of NF-κB ligand (RANKL) and tumor necrosis factor α (TNF-α) using macrophage cell lines …

Background—Nuclear factor κB (NF-κB) is often implicated in contributing to the detrimental
effects of cardiac injury. This ostensibly negative view of NF-κB competes with its important …

Background—Overexpression of receptor activator of nuclear factor-κB ligand (RANKL) is a
prominent feature of vulnerable atherosclerotic lesions prone to rupture and was thought to …

The maintenance of endothelial integrity is important for prevention of vascular diseases.
Several growth factors, such as bFGF and angiopoietin‐1, have been shown to suppress …

By virtue of their actions on NF-κB, an inflammatory nuclear transcription factor, various
cytokines have been documented to play important regulatory roles in determining cardiac …