Herpes B Virus, Macacine Herpesvirus 1, Breaks Simplex Virus Tradition via Major Histocompatibility Complex Class I Expression in Cells from Human and Macaque …

M Vasireddi, J Hilliard - Journal of virology, 2012 - Am Soc Microbiol
ABSTRACT B virus of the family Herpesviridae is endemic to rhesus macaques but results in
80% fatality in untreated humans who are zoonotically infected. Downregulation of major …

Human herpesvirus 7 u21 downregulates classical and nonclassical class I major histocompatibility complex molecules from the cell surface

NA May, NL Glosson, AW Hudson - Journal of virology, 2010 - Am Soc Microbiol
Herpesviruses have evolved numerous strategies to evade detection by the immune system.
Notably, most of the herpesviruses interfere with viral antigen presentation to cytotoxic T …

The switch from latent to productive infection in Epstein-Barr virus-infected B cells is associated with sensitization to NK cell killing

IY Pappworth, EC Wang, M Rowe - Journal of virology, 2007 - Am Soc Microbiol
ABSTRACT Following activation of Epstein-Barr virus (EBV)-infected B cells from latent to
productive (lytic) infection, there is a concomitant reduction in the level of cell surface major …

B virus (Macacine Herpesvirus 1) divergence: variations in glycoprotein D from clinical and laboratory isolates diversify virus entry strategies

I Patrusheva, L Perelygina, I Torshin, J LeCher… - Journal of …, 2016 - Am Soc Microbiol
ABSTRACT B virus (Macacine herpesvirus 1) can cause deadly zoonotic disease in
humans. Molecular mechanisms of B virus cell entry are poorly understood for both …

B virus (Macacine herpesvirus 1) glycoprotein D is functional but dispensable for virus entry into macaque and human skin cells

L Perelygina, I Patrusheva, M Vasireddi… - Journal of …, 2015 - Am Soc Microbiol
Glycoprotein D (gD) plays an essential role in cell entry of many simplexviruses. B virus
(Macacine herpesvirus 1) is closely related to herpes simplex virus 1 (HSV-1) and encodes …

Towards a comprehensive view of the herpes B virus

J Lu, Y Long, J Sun, L Gong - Frontiers in Immunology, 2023 - frontiersin.org
Herpes B virus is a biosafety level 4 pathogen and widespread in its natural host species,
macaques. Although most infected monkeys show asymptomatic or mild symptoms, human …

Glycoprotein B from strain 17 of herpes simplex virus type I contains an invariant chain homologous sequence that binds to MHC class II molecules

E Sievers, J Neumann, M Raftery, G SchÖnrich… - …, 2002 - Wiley Online Library
Major histocompatibility complex class I (MHCI) molecules are major targets of virus evasion
strategies because they introduce antigens from the biosynthesis pathway into the antigen …

Immune Control of γ-Herpesviruses

PG Stevenson - Viral Immunology, 2020 - liebertpub.com
Vaccination against γ-herpesviruses has been hampered by our limited understanding of
their normal control. Epstein–Barr virus (EBV)-transformed B cells are killed by viral latency …

[HTML][HTML] Viral modulation of the host response to infection

AL McCormick, ES Mocarski Jr - Human herpesviruses: biology …, 2007 - ncbi.nlm.nih.gov
Betaherpesviruses such as HCMV dramatically affect host cell physiology and encode a
wide variety of functions that modulate the infected host cell as well as the immune response …

[HTML][HTML] Multiple endocytic trafficking pathways of MHC class I molecules induced by a Herpesvirus protein

RE Means, S Ishido, X Alvarez, JU Jung - The EMBO journal, 2002 - embopress.org
The K3 protein of a human tumor‐inducing herpesvirus, Kaposi's sarcoma‐associated
herpesvirus (KSHV), down‐regulates major histocompatibility complex (MHC) class I surface …