Ancient DNA studies: new perspectives on old samples

E Rizzi, M Lari, E Gigli, G De Bellis… - Genetics Selection …, 2012 - Springer
In spite of past controversies, the field of ancient DNA is now a reliable research area due to
recent methodological improvements. A series of recent large-scale studies have revealed …

The future of ancient DNA: technical advances and conceptual shifts

M Hofreiter, JLA Paijmans, H Goodchild… - …, 2015 - Wiley Online Library
Technological innovations such as next generation sequencing and DNA hybridisation
enrichment have resulted in multi‐fold increases in both the quantity of ancient DNA …

Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

ancient DNA

M Hofreiter, D Serre, HN Poinar, M Kuch… - Nature Reviews …, 2001 - nature.com
DNA that has been recovered from archaeological and palaeontological remains makes it
possible to go back in time and study the genetic relationships of extinct organisms to their …

Evolutionary patterns and processes: lessons from ancient DNA

M Leonardi, P Librado, C Der Sarkissian… - Systematic …, 2017 - academic.oup.com
Ever since its emergence in 1984, the field of ancient DNA has struggled to overcome the
challenges related to the decay of DNA molecules in the fossil record. With the recent …

New uses for old DNA

A Cooper, R Wayne - Current Opinion in Biotechnology, 1998 - Elsevier
Several years have elapsed since the last report of million-year-old DNA, coinciding with
increased standards for experimental procedures in ancient DNA research. Whereas many …

A paleogenomic perspective on evolution and gene function: new insights from ancient DNA

B Shapiro, M Hofreiter - Science, 2014 - science.org
Background After three decades of research aimed at recovering DNA from preserved
remains, the field of ancient DNA is moving rapidly toward the sequencing and analysis of …

A rapid column‐based ancient DNA extraction method for increased sample throughput

N Rohland, H Siedel, M Hofreiter - Molecular ecology …, 2010 - Wiley Online Library
Genetic analyses using museum specimens and ancient DNA from fossil samples are
becoming increasingly important in phylogenetic and especially population genetic studies …

Next generation sequencing of ancient DNA: requirements, strategies and perspectives

M Knapp, M Hofreiter - Genes, 2010 - mdpi.com
The invention of next-generation-sequencing has revolutionized almost all fields of genetics,
but few have profited from it as much as the field of ancient DNA research. From its …

Ancient dna

E Willerslev, A Cooper - Proceedings of the Royal …, 2005 - royalsocietypublishing.org
In the past two decades, ancient DNA research has progressed from the retrieval of small
fragments of mitochondrial DNA from a few late Holocene specimens, to large-scale studies …