P2X receptors are ligand‐gated cation channels that mediate many of the extracellular
actions of adenosine 5′‐triphosphate (ATP). The genes encoding seven different P2X …

P2X receptors for adenosine tri-phosphate (ATP) are a distinct family of ligand-gated cation
channels with two transmembrane domains, intracellular amino and carboxy termini and a …

P2X receptors are membrane ion channels that open in response to the binding of
extracellular ATP. Seven genes in vertebrates encode P2X receptor subunits, which are 40 …

The known seven mammalian receptor subunits (P2X1–7) form cationic channels gated by
ATP. Three subunits compose a receptor channel. Each subunit is a polypeptide consisting …

P2X receptors are a family of ion channels gated by extracellular ATP. Each member of the
family can form functional homomeric channels, but only P2X2 and P2X3 have been shown …

Extracellular adenosine 5′-triphosphate (ATP) activates cell surface P2X and P2Y
receptors. P2X receptors are membrane ion channels preferably permeable to sodium …

ATP acts as a humoral mediator to control cell function extracellularly. The receptors that
mediate the actions of ATP belong to two classes, the metabotropic P2Y receptors and the …

P2X receptors are ligand-gated ion channels that transduce many of the physiological
effects of extracellular ATP. There has been a dramatic increase in awareness of these …

ATP functions as a fast neurotransmitter through the specific activation of a family of ligand-
gated ion channels termed P2X receptors. In this report, six distinct recombinant P2X …

P2X receptors comprise a family of ATP-gated ion channels with the basic amino acids Lys-
68, Arg-292, and Lys-309 (P2X 1 receptor numbering) contributing to agonist potency. In …