With unprecedented development in technology, epigenetics is recognized as a substantial
and flexible regulatory pathway for phenotyping. Cytosine methylation and its subsequent …

DNA methylation and histone modifications are central to epigenetic gene regulation, which
has been shown to play a crucial role in development. Epigenetics has often been …

Abstract Argonaute 2 (Ago2) is a pivotal regulator of cell fate in adult stem cells. Its
expression is significantly downregulated in late passages of cells, concomitant with a …

Gallbladder cancer (GBC) is a lethal and a common malignancy affecting mostly females.
There are restricted high incidence pockets across the world and in northern India highest …

Chromatin is the packaged form of the eukaryotic genome in the cell nucleus, presenting the
substrate for all DNA dependent processes. The basic packaging unit of chromatin is the …

The upstream Gγ-globin cAMP-response element (G-CRE) plays an important role in
regulating Gγ-globin expression through binding of ATF2 and its DNA-binding partners …

In this chapter we will concentrate on the transcriptional and translational regulations that
govern the development and differentiation of male germline cells. Our focus will be on the …

Background Many studies have suggested different roles of Metastasis-associated protein 3
(MAT3) in different types of human cancers. However, expression of MAT3 in primary lung …

Background. Promoter methylation is associated with gene repression; however, little is
known about its mechanism. It was proposed that the repression of methylated genes is …

Forkhead box L2 (Foxl2), a member of the forkhead transcription factor family, plays
important roles in pituitary follicle-stimulating hormone synthesis and in ovarian …