The mammalian immune system has two main components: innate and adaptive. The innate
immune system is composed of cells such as neutrophils, dendritic cells, natural killer (NK) …

CD4+ T cells developing toward a Th2 fate express IL-4, IL-5, and IL-13 while inhibiting
production of cytokines associated with other Th types, such as the Th1 cytokine IFN-γ. IL-4 …

Summary In Arabidopsis thaliana, HISTONE DEACETYLASE 6 (HDA6) plays a crucial role
in gene silencing. To further understand the molecular mechanisms underlying HDA6 …

Erogullari A., Osmanovic A., Rakovic A., Orolicki S., Braunholz D., Lohnau T., Albrecht M.,
Gillessen-Kaesbach G., Klein C., Lohmann K., Kaiser FJ A functional link of DYT1 and DYT6 …

This PhD thesis is a biochemical and structural analysis of elements and interactions of the
Nucleosome Remodelling and Deacetylase (NuRD) complex. Chapter 1 presents a general …

Abstract Chromatin Assembly Factor 1 (CAF-1) is the only known replication dependant
histone chaperone, responsible for the deposition of the histone H3/H4 tetramer onto DNA …

Abstract The Polycomb Repressor Complex (PRC) is an epigenetic regulator of transcription
whose action is mediated by two protein complexes, PRC1 and PRC2. PRC activity normally …

BMC Bone mineral content BMP Bone morphogenic protein BMPR Autoinducer-binding
transcriptional regulator BMPRIA/BMPRIB BMP type IA receptor (and type IB receptor) Bsp …

Despite a better understanding of its molecular pathogenesis and advances in developing
new treatment strategies, lung cancer is still one of the leading causes of cancer-related …

abstract Planarian adult stem cells (pASCs) or neoblasts represent an ideal system to study
the evolution of stem cells and pluripotency as they underpin an unrivaled capacity for …