Ischemic stroke is a devastating condition, for which there is still no effective therapy. Acute
ischemic stroke is associated with high concentrations of glutamate in the blood and …

Honokiol, a major bioactive constituent of the bark of Magnolia officinalis has been
confirmed to have the neuroprotective effect on ischemic stroke in rats. This study was …

Early recanalisation and an increase in collateral blood supply are predictors of favourable
outcome in acute ischaemic stroke. Since individual responses to intravenous treatment with …

Stroke is a major cause of mortality and disability worldwide. The main cause of stroke is
atherosclerosis, and the most common risk factor for atherosclerosis is hypertension …

Hibernating squirrels slow blood flow to a crawl, but sustain no damage to brain or other
tissues. This phenomenon provides an excellent model of natural tolerance to ischemia …

This work reviews the neuropharmacology of the vestibular system, with an emphasis on the
mechanism of action of drugs used in the treatment of vestibular disorders. Clinicians are …

Key points• The redox‐sensitive transcription factor NF‐E2 related factor 2 (Nrf2) plays a key
role in regulating adaptive cellular antioxidant defences, and activation of Nrf2 in stroke …

Although stroke is one of the leading causes of death and disability worldwide, preventive or
therapeutic options are still limited. Therefore, a better understanding of the …

Increased level of endothelin-1 (ET-1), a potent vasoconstrictor, has been found in the
cerebral spinal fluid (CSF) of patients with multi-infarction dementia, suggesting a possible …

Some macrophages expressing NG2 chondroitin sulfate proteoglycan (NG2) and the
macrophage marker Iba1 accumulate in the ischemic core of a rat brain subjected to …