Translational research frequently fails to replicate in the clinic what has been demonstrated
in the laboratory. This has been true for neuroprotection in the central nervous system …

Glaucoma, a disease of the optic nerve and retina, causes blindness in millions of people
worldwide. Currently available therapies for this disease only attempt to reduce intraocular …

Introduction Animal models are widely used in glaucoma-related research. Since the
elevated intraocular pressure (IOP) is a major risk factor underlying the disease …

Purpose Neuroprotection aims to treat nervous system disease by maintaining the health
and function of neurons. The final proof of the neuroprotective strategy relies on randomized …

Purpose: The eye is currently at the forefront of translational medicine and therapeutics.
However, despite advances in technology, primary open-angle glaucoma remains the …

Given that glaucoma is a disease of the central nervous system, there must be greater
emphasis and focus on developing intraocular pressure–independent therapies. In addition …

Neuroprotection is a therapeutic approach that aims to prevent neuronal degeneration and
loss of function. Research has focused on developing neuroprotective agents for the therapy …

Glaucoma is the leading cause of irreversible blindness globally. The disease causes vision
loss due to neurodegeneration of the retinal ganglion cell (RGC) projection to the brain …

Developing successful drug delivery methods is challenging for any tissue, and the eye is no
exception. Translating initial concepts into advanced technologies treating diseases in …

Neuroprotection in glaucoma: recent and future directions : Current Opinion in Ophthalmology
Neuroprotection in glaucoma: recent and future directions : Current Opinion in Ophthalmology …