Argonaute and Triman generate dicer-independent priRNAs and mature siRNAs to initiate heterochromatin formation
M Marasovic, M Zocco, M Halic - Molecular cell, 2013 - cell.com
RNAi is a conserved mechanism in which small RNAs induce silencing of complementary
targets. We have previously identified priRNAs, a class of Dicer-independent small RNAs in …
targets. We have previously identified priRNAs, a class of Dicer-independent small RNAs in …
[HTML][HTML] Dicer-independent primal RNAs trigger RNAi and heterochromatin formation
M Halic, D Moazed - Cell, 2010 - cell.com
Assembly of fission yeast pericentromeric heterochromatin and generation of small
interfering RNAs (siRNAs) from noncoding centromeric transcripts are mutually dependent …
interfering RNAs (siRNAs) from noncoding centromeric transcripts are mutually dependent …
Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast
F Simmer, A Buscaino, IC Kos‐Braun, A Kagansky… - EMBO …, 2010 - embopress.org
RNA interference (RNAi) is widespread in eukaryotes and regulates gene expression
transcriptionally or post‐transcriptionally. In fission yeast, RNAi is tightly coupled to template …
transcriptionally or post‐transcriptionally. In fission yeast, RNAi is tightly coupled to template …
TRAMP-mediated RNA surveillance prevents spurious entry of RNAs into the Schizosaccharomyces pombe siRNA pathway
In the fission yeast Schizosaccharomyces pombe, the RNA interference (RNAi) machinery is
required to generate small interfering RNAs (siRNAs) that mediate heterochromatic gene …
required to generate small interfering RNAs (siRNAs) that mediate heterochromatic gene …
Analysis of small RNA in fission yeast; centromeric siRNAs are potentially generated through a structured RNA
I Djupedal, IC Kos‐Braun, RA Mosher… - The EMBO …, 2009 - embopress.org
The formation of heterochromatin at the centromeres in fission yeast depends on
transcription of the outer repeats. These transcripts are processed into siRNAs that target …
transcription of the outer repeats. These transcripts are processed into siRNAs that target …
A novel RNAi protein, Dsh1, assembles RNAi machinery on chromatin to amplify heterochromatic siRNA
K Kawakami, A Hayashi, J Nakayama… - Genes & …, 2012 - genesdev.cshlp.org
In fission yeast, siRNA is generated from pericentromeric noncoding RNA by the RNAi
machinery. siRNA synthesis and heterochromatin formation are interdependent, forming a …
machinery. siRNA synthesis and heterochromatin formation are interdependent, forming a …
Tailing and degradation of Argonaute-bound small RNAs protect the genome from uncontrolled RNAi
P Pisacane, M Halic - Nature communications, 2017 - nature.com
RNAi is a conserved mechanism in which small RNAs induce silencing of complementary
targets. How Argonaute-bound small RNAs are targeted for degradation is not well …
targets. How Argonaute-bound small RNAs are targeted for degradation is not well …
Coupling of double-stranded RNA synthesis and siRNA generation in fission yeast RNAi
SU Colmenares, SM Buker, M Buhler, M Dlakić… - Molecular cell, 2007 - cell.com
The fission yeast centromeric repeats are transcribed and ultimately processed into small
interfering RNAs (siRNAs) that are required for heterochromatin formation. siRNA …
interfering RNAs (siRNAs) that are required for heterochromatin formation. siRNA …
RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe
A Smialowska, I Djupedal, J Wang, P Kylsten… - Biochemical and …, 2014 - Elsevier
RNA interference (RNAi) is a gene silencing mechanism conserved from fungi to mammals.
Small interfering RNAs are products and mediators of the RNAi pathway and act as …
Small interfering RNAs are products and mediators of the RNAi pathway and act as …
[PDF][PDF] Common themes in siRNA-mediated epigenetic silencing pathways.
A Verdel, A Vavasseur, M Le Gorrec… - International Journal of …, 2009 - Citeseer
Small interfering RNAs (siRNAs) act through RNA interference (RNAi) pathways to silence
gene expression either at the transcriptional or post-transcriptional level. Here, we review …
gene expression either at the transcriptional or post-transcriptional level. Here, we review …