Nephron morphogenesis is a complex process that generates blood-filtration units
(glomeruli) connected to extremely long and patterned tubular structures. Hepatocyte …

Hepatocyte nuclear factor-1β (HNF-1β) is an essential transcription factor that regulates the
development and function of epithelia in the kidney, liver, pancreas, and genitourinary tract …

The homeobox transcription factor hepatocyte nuclear factor 1β (HNF1β) is a tissue-specific
regulator that plays an essential role in early vertebrate development. In humans …

Heterozygous mutations in the gene that encodes the transcription factor hepatocyte nuclear
factor 1β (HNF1B) represent the most common known monogenic cause of developmental …

The transcription factor hepatocyte nuclear factor 1β (HNF1β) is a tissue-specific regulator
that also plays an essential role in early development of vertebrates. In humans, four …

Abnormal nephron development associated with a frameshift mutation in the transcription
factor hepatocyte nuclear factor-1β. Background The transcription factor hepatocyte nuclear …

The hepatocyte nuclear factor—1β (HNF-1β) transcription factor controls endoderm
development. Human mutations cause early-onset diabetes mellitus and have recently been …

The nephron is a highly specialised segmented structure that provides essential filtration
and resorption renal functions. It arises by formation of a polarised renal vesicle that …

Nephrons comprise a blood filter and an epithelial tubule that is subdivided into proximal
and distal segments, but what directs this patterning during kidney organogenesis is not well …

Heterozygous mutations of the tissue-specific transcription factor hepatocyte nuclear factor
(HNF) 1β, cause maturity onset diabetes of the young (MODY5) and kidney anomalies …