Evaluation of the role of MAPK1 and CREB1 polymorphisms on treatment resistance, response and remission in mood disorder patients
R Calati, C Crisafulli, M Balestri, A Serretti… - Progress in Neuro …, 2013 - Elsevier
Treatment resistant depression (TRD) is a significant clinical and public health problem.
Among others, neuroplasticity and inflammatory pathways seem to play a crucial role in the …
Among others, neuroplasticity and inflammatory pathways seem to play a crucial role in the …
A preliminary investigation of the influence of CREB1 gene on treatment resistance in major depression
A Serretti, A Chiesa, R Calati, I Massat, S Linotte… - Journal of affective …, 2011 - Elsevier
BACKGROUND: The transcription factor Cyclic adenosine monophosphate Response
Element Binding (CREB) protein has been repeatedly involved in the aetiology and …
Element Binding (CREB) protein has been repeatedly involved in the aetiology and …
Neuroplasticity and second messenger pathways in antidepressant efficacy: pharmacogenetic results from a prospective trial investigating treatment resistance
Genes belonging to neuroplasticity, monoamine, circadian rhythm, and transcription factor
pathways were investigated as modulators of antidepressant efficacy. The present study …
pathways were investigated as modulators of antidepressant efficacy. The present study …
Genetic variation in the calcium/calmodulin-dependent protein kinase (CaMK) pathway is associated with antidepressant response in females
Y Shi, Y Yuan, Z Xu, M Pu, C Wang, Y Zhang… - Journal of affective …, 2012 - Elsevier
OBJECTIVE: Antidepressant effects on monoamine neurotransmission may be influenced by
genetic variation in intracellular signal transduction pathways, such as the cyclic adenosine …
genetic variation in intracellular signal transduction pathways, such as the cyclic adenosine …
Case–control association study of 14 variants of CREB1, CREBBP and CREM on diagnosis and treatment outcome in major depressive disorder and bipolar disorder
C Crisafulli, DS Shim, C Andrisano, CU Pae… - Psychiatry …, 2012 - Elsevier
Some evidence suggests an association between genetic variants within the cyclic
adenosine monophosphate (cAMP) response element-binding protein (CREB), CREB …
adenosine monophosphate (cAMP) response element-binding protein (CREB), CREB …
NRG1, PIP4K2A, and HTR2C as Potential Candidate Biomarker Genes for Several Clinical Subphenotypes of Depression and Bipolar Disorder
A Levchenko, NM Vyalova, T Nurgaliev… - Frontiers in …, 2020 - frontiersin.org
GSK3B, BDNF, NGF, NRG1, HTR2C, and PIP4K2A play important roles in molecular
mechanisms of psychiatric disorders. GSK3B occupies a central position in these molecular …
mechanisms of psychiatric disorders. GSK3B occupies a central position in these molecular …
A splice site polymorphism in the G-protein β subunit influences antidepressant efficacy in depression
Objective Recent evidence suggests that signalling cascades located downstream of
monoamine receptors are altered following antidepressant treatment. Our objective was to …
monoamine receptors are altered following antidepressant treatment. Our objective was to …
[HTML][HTML] Genes involved in neurodevelopment, neuroplasticity and major depression: no association for CACNA1C, CHRNA7 and MAPK1
M Calabrò, L Mandelli, C Crisafulli, SJ Lee… - Clinical …, 2019 - ncbi.nlm.nih.gov
Objective Genetics factors are likely to play a role in the risk, clinical presentation and
treatment outcome in major depressive disorder (MDD). In this study, we investigated the …
treatment outcome in major depressive disorder (MDD). In this study, we investigated the …
The Impact of BDNF, NTRK2, NGFR, CREB1, GSK3B, AKT, MAPK1, MTOR, PTEN, ARC, and SYN1 Genetic Polymorphisms in Antidepressant Treatment …
This study aimed to investigate the influence of genetic variants in neuroplasticity-related
genes on antidepressant treatment phenotypes. The BDNF-TrkB signaling pathway, as well …
genes on antidepressant treatment phenotypes. The BDNF-TrkB signaling pathway, as well …
Polymorphisms of COMT and CREB1 are associated with treatment-resistant depression in a Chinese Han population
Y Wang, S Li, L Niu, Y Ma, Y Qiu, S Li… - Journal of Neural …, 2022 - Springer
Genetic factors play a crucial role for the pathophysiology of treatment-resistant depression
(TRD). It has been established that Catechol-O-methyltransferase (COMT) and cyclic amp …
(TRD). It has been established that Catechol-O-methyltransferase (COMT) and cyclic amp …