Recent developments in the study of epithelial ovarian cancer have called into question the
traditional views regarding the site of tumor initiation. Histopathologic studies and genomic …

High-grade serous ovarian carcinoma (HGSOC) is a lethal disease for which improved
screening and treatment strategies are urgently needed. Progress in these areas is impeded …

The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial,
with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered …

Unlike other human cancers, in which all primary tumors arise de novo, ovarian epithelial
cancers are primarily imported from either endometrial or fallopian tube epithelium. The …

The present review focuses on the current status of molecular pathology in high‑grade
serous cancer (HGSC) and preneoplastic conditions. This article reviews the English …

Fallopian tube secretory epithelial cells (FTSECs) are likely the main precursor cell type of
high-grade serous ovarian cancers (HGSOCs), but these tumors may also arise from ovarian …

High‐grade serous carcinoma (HGSC) is the most common and malignant histological type
of epithelial ovarian cancer, the origin of which remains controversial. Currently, the …

Accumulating evidence has supported the fallopian tube rather than the ovary as the origin
for high-grade serous ovarian cancer (HGSOC). To understand the relationship between …

Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we
provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first …

High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecological
malignancy. To date, the profiles of gene mutations and copy number alterations in HGSOC …