Background: Guidelines suggest a plateau pressure (P plat) of 30 cm H2O or less for
patients with acute respiratory distress syndrome, but ventilation may still be injurious …

Background: It has been suggested that higher positive end-expiratory pressure (PEEP)
should be used only in patients with higher lung recruitability. In this study, the authors …

Objective: Previously published methods to assess the chest wall effect on total respiratory
system pressure-volume (PV) curves in acute respiratory distress syndrome have been …

Objectives: Although there is general agreement on the characteristic features of the acute
respiratory distress syndrome, we lack a scoring system that predicts acute respiratory …

Rationale: Current American-European Consensus Conference definitions for acute lung
injury (ALI) and acute respiratory distress syndrome (ARDS) are inadequate for inclusion …

Background Static pressure-volume (PV) curves have been promoted as a tool for selecting
positive end-expiratory pressure (PEEP) by identifying a lower" inflection point"(P flex) from …

Abstract Background The current Berlin definition of acute respiratory distress syndrome
(ARDS) uses the PaO2/FiO2 (P/F) ratio to classify severity. However, for the same P/F ratio, a …

Mechanical impairment of the respiratory system was recognised soon after the description
of acute respiratory distress syndrome. The analysis of the pressure/volume (P/V) curve of …

The inflection points of the pressure–volume curve have been used for setting mechanical
ventilation in patients with acute lung injury. However, the lung status at these points has …

Measurement of pressure–volume curves at the bedside in critically ill patients with acute
lung injury or acute respiratory distress syndrome should be considered a useful respiratory …