[HTML][HTML] Intra-epithelial requirement of canonical Wnt signaling for tooth morphogenesis

XJ Zhu, P Zhao, YD Liu, XY Zhang, J Fu, HMI Yu… - Journal of Biological …, 2013 - ASBMB
Multiple Wnt ligands are expressed in the developing tooth and play important and
redundant functions during odontogenesis. However, the source of Wnt ligands and their …

Wnt production in dental epithelium is crucial for tooth differentiation

Y Xiong, Y Fang, Y Qian, Y Liu, X Yang… - Journal of dental …, 2019 - journals.sagepub.com
The Wnt ligands display varied spatiotemporal expression in the epithelium and
mesenchyme in the developing tooth. Thus far, the actions of these differentially expressed …

Wntless regulates dentin apposition and root elongation in the mandibular molar

CH Bae, TH Kim, SO Ko, JC Lee… - Journal of Dental …, 2015 - journals.sagepub.com
Wnt signaling plays an essential role in the dental epithelium and mesenchyme during tooth
morphogenesis. However, it remains unclear if Wnt ligands, produced from dental …

Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth

M Lin, L Li, C Liu, H Liu, F He, F Yan… - Developmental …, 2011 - Wiley Online Library
Wnt/β‐catenin signaling is essential for tooth development beyond the bud stage, but little is
known about the role of non‐canonical Wnt signaling in odontogenesis. Here we compared …

Over-and ectopic expression of Wnt3 causes progressive loss of ameloblasts in postnatal mouse incisor teeth

SE Millar, E Koyama, ST Reddy, T Andl… - Connective tissue …, 2003 - Taylor & Francis
Intercellular signaling is essential for the development of teeth during embryogenesis and in
maintenance of the continuously growing incisor teeth in postnatal rodents. WNT …

Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/β‐catenin signaling in the epithelial stem cells

M Suomalainen, I Thesleff - Developmental dynamics: an …, 2010 - Wiley Online Library
The Wnt pathway is crucial for tooth development as shown by dental defects caused by
impaired Wnt signaling in mouse and human. We investigated Wnt signaling in continuously …

[HTML][HTML] Wnt/β-catenin signaling directs multiple stages of tooth morphogenesis

F Liu, EY Chu, B Watt, Y Zhang, NM Gallant, T Andl… - Developmental …, 2008 - Elsevier
Wnt/β-catenin signaling plays key roles in tooth development, but how this pathway
intersects with the complex interplay of signaling factors regulating dental morphogenesis …

Early perturbation of Wnt signaling reveals patterning and invagination-evagination control points in molar tooth development

R Kim, T Yu, J Li, J Prochazka, A Sharir… - …, 2021 - journals.biologists.com
Tooth formation requires complex signaling interactions both within the oral epithelium and
between the epithelium and the underlying mesenchyme. Previous studies of the Wnt/β …

[HTML][HTML] Role of the Wnt signaling molecules in the tooth

M Tamura, E Nemoto - Japanese Dental Science Review, 2016 - Elsevier
Wnt signaling plays a central role in many processes during embryonic development and
adult homeostasis. At least 19 types of Wnt ligands, receptors, transducers, transcription …

[HTML][HTML] Intertwined signaling pathways governing tooth development: a give-and-take between canonical Wnt and Shh

F Hermans, L Hemeryck, I Lambrichts… - Frontiers in cell and …, 2021 - frontiersin.org
Teeth play essential roles in life. Their development relies on reciprocal interactions
between the ectoderm-derived dental epithelium and the underlying neural crest-originated …