CD8+ T cell immune responses provide immediate protection against primary infection and
durable memory capable of rapidly fighting off re-infection. Immediate protection and lasting …

In response to infection or effective vaccination, naive antigen‐specific CD8+ T cells
undergo a dramatic highly orchestrated activation process. Initial encounter with an …

One outcome of infection is the formation of long-lived immunological memory, which
provides durable protection from symptomatic re-infection. In response to infection or …

Immune protection and lasting memory are accomplished through the generation of
phenotypically and functionally distinct CD8 T cell subsets. Understanding how these …

Long-term immunological protection relies on the differentiation and maintenance of
memory lymphocytes. Since the knowledge of memory generation has been centered on in …

CD8+ T cell immunological memory of past antigen exposure can confer long-lived
protection against infections or tumors. The fact that CD8+ memory T cells can have features …

During an infection, T cells can differentiate into multiple types of effector and memory T
cells, which help to mediate pathogen clearance and provide long-term protective immunity …

Vaccines, arguably the single most important intervention in improving human health, have
exploited the phenomenon of immunological memory. The elicitation of memory T cells is …

Memory differentiation of CD4 and CD8 T-cell populations has been extensively studied and
many key molecular players and transcriptional networks have been identified. But how …

The immune system, smartly and surprisingly, saves the exposure of a particular pathogen
in its memory and reacts to the pathogen very rapidly, preventing serious diseases …