Pathophysiology and clinical implications of pulmonary arterial enlargement in COPD

JM Wells, MT Dransfield - International journal of chronic …, 2013 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a complex condition defined by
progressive airflow limitation in response to noxious stimuli, inflammation, and vascular …

[HTML][HTML] Pulmonary arterial enlargement predicts long-term survival in COPD patients

JP de-Torres, A Ezponda, AB Alcaide, A Campo… - PLoS …, 2018 - journals.plos.org
Rationale Pulmonary artery enlargement (PAE) is associated with exacerbations in Chronic
Obstructive Pulmonary Disease (COPD) and with survival in moderate to severe patients …

[HTML][HTML] Pulmonary arterial enlargement and acute exacerbations of COPD

JM Wells, GR Washko, MLK Han… - New England journal …, 2012 - Mass Medical Soc
Background Exacerbations of chronic obstructive pulmonary disease (COPD) are
associated with accelerated loss of lung function and death. Identification of patients at risk …

Pulmonary artery enlargement and mortality risk in moderate to severe COPD: results from COPDGene

DC LaFon, SP Bhatt, WW Labaki… - European …, 2020 - Eur Respiratory Soc
COPD is one of the leading causes of mortality worldwide [1]. Pulmonary hypertension has
been associated with reduced survival among individuals with COPD [2] and is an …

Usefulness of the 6-minute walk test as a screening test for pulmonary arterial enlargement in COPD

Y Oki, M Kaneko, Y Fujimoto, H Sakai… - … journal of chronic …, 2016 - Taylor & Francis
Purpose Pulmonary hypertension and exercise-induced oxygen desaturation (EID)
influence acute exacerbation of COPD. Computed tomography (CT)-detected pulmonary …

[HTML][HTML] Pulmonary artery size as a predictor of pulmonary hypertension and outcomes in patients with chronic obstructive pulmonary disease

S Shin, CS King, AW Brown, MC Albano, M Atkins… - Respiratory …, 2014 - Elsevier
Rationale The relationship between pulmonary artery size with underlying pulmonary
hypertension and mortality remains to be determined in COPD. We sought to evaluate the …

Pulmonary artery enlargement is associated with right ventricular dysfunction and loss of blood volume in small pulmonary vessels in chronic obstructive pulmonary …

JM Wells, AS Iyer, FN Rahaghi, SP Bhatt… - Circulation …, 2015 - Am Heart Assoc
Background—Chronic obstructive pulmonary disease causes significant morbidity and
concomitant pulmonary vascular disease and cardiac dysfunction are associated with poor …

Pulmonary artery enlargement is associated with cardiac injury during severe exacerbations of COPD

JM Wells, JB Morrison, SP Bhatt, H Nath, MT Dransfield - Chest, 2016 - Elsevier
Background Relative pulmonary arterial enlargement, defined by a pulmonary artery to aorta
(PA/A) ratio> 1 on CT scanning, predicts hospitalization for acute exacerbations of COPD …

CT scan-measured pulmonary artery to aorta ratio and echocardiography for detecting pulmonary hypertension in severe COPD

AS Iyer, JM Wells, S Vishin, SP Bhatt, KM Wille… - Chest, 2014 - Elsevier
Background COPD is associated with significant morbidity primarily driven by acute
exacerbations. Relative pulmonary artery (PA) enlargement, defined as a PA to ascending …

Co-existence of COPD and bronchiectasis: a risk factor for a high ratio of main pulmonary artery to aorta diameter (PA: A) from computed tomography in COPD …

S Dou, C Zheng, X Ji, W Wang, M Xie… - International journal of …, 2018 - Taylor & Francis
Background Pulmonary vascular disease, especially pulmonary hypertension, is an
important complication of COPD. Bronchiectasis is considered not only a comorbidity of …