IgE antibody-mediated allergies affect more than 25% of the population worldwide. To
investigate therapeutic and preventive effects of passive immunization with allergen-specific …

Molecular characterization of allergens by recombinant DNA technology has made rapid
progress in the recent few years. In the present study we immunized mice with aluminum …

The induction of allergen-specific IgG antibodies has been identified as a major mechanism
responsible for the reduction of allergic inflammation in allergic patients treated by allergen …

BACKGROUND: Among atopic individuals, levels of allergen-specific IgG antibodies have
been inversely associated with the degree of allergen sensitization. Additionally, allergen …

Background: The induction of nonanaphylactogenic 'blocking'IgG antibodies capable of
inhibiting the IgE/allergen interaction represents a favorable therapeutic concept for type I …

Immunoglobulin E (IgE)-associated allergy is the most common immunologically-mediated
hypersensensitivity disease. It is based on the production of IgE antibodies and T cell …

BACKGROUND: We have performed a double-blind, placebo-controlled injection
immunotherapy study with genetically modified derivatives of the major birch pollen …

Allergen-specific IgG antibodies play a significant role in allergen-specific tolerance, either
naturally induced or generated by specific immunotherapy. Nevertheless, the underlying …

Background Allergen‐specific immunotherapy (AIT) induces specific blocking antibodies
(Ab), which are claimed to prevent IgE‐mediated reactions to allergens. Additionally, AIT …

Immunoglobulin E (IgE)‐mediated allergy is the most common hypersensitivity disease
affecting more than 30% of the population. Exposure to even minute quantities of allergens …