Micro-Autoradiographic Assessment of Cell Types Contributing to 2-Deoxy-2-[18F]Fluoro-d-Glucose Uptake During Ventilator-Induced and Endotoxemic Lung Injury

D Saha, K Takahashi, N de Prost, T Winkler… - Molecular imaging and …, 2013 - Springer
Purpose The aim of the study was to use micro-autoradiography to investigate the lung cell
types responsible for 2-deoxy-2-[18 F] fluoro-d-glucose (FDG) uptake in murine models of …

18F-fluoro-2-deoxyglucose PET informs neutrophil accumulation and activation in lipopolysaccharide-induced acute lung injury

RS Rodrigues, FA Bozza, CJ Hanrahan… - Nuclear medicine and …, 2017 - Elsevier
Introduction Molecular imaging of the earliest events related to the development of acute
lung injury (ALI)/acute respiratory distress syndrome (ARDS) could facilitate therapeutic …

Molecular imaging of lung glucose uptake after endotoxin in mice

Z Zhou, J Kozlowski, AL Goodrich… - … of Physiology-Lung …, 2005 - journals.physiology.org
Positron emission tomographic imaging after administration of the glucose analog fluorine-
18 fluorodeoxyglucose ([18F] FDG) may be useful to study neutrophilic inflammation of the …

Modeling pulmonary kinetics of 2-deoxy-2-[18F] fluoro-D-glucose during acute lung injury

T Schroeder, MFV Melo, G Musch, RS Harris… - Academic radiology, 2008 - Elsevier
RATIONALE AND OBJECTIVES: Dynamic positron emission tomographic imaging of the
radiotracer 2-deoxy-2-[18F] fluoro-d-glucose (18F-FDG) is increasingly used to assess …

Early inflammation mainly affects normally and poorly aerated lung in experimental ventilator-induced lung injury

JB Borges, ELV Costa, F Suarez-Sipmann… - Critical care …, 2014 - journals.lww.com
Objective: The common denominator in most forms of ventilator-induced lung injury is an
intense inflammatory response mediated by neutrophils. PET with [18 F] fluoro-2-deoxy-D …

18F-FDG kinetics parameters depend on the mechanism of injury in early experimental acute respiratory distress syndrome

N De Prost, Y Feng, T Wellman, MR Tucci… - Journal of Nuclear …, 2014 - Soc Nuclear Med
PET with 18F-FDG allows for noninvasive assessment of regional lung metabolism reflective
of neutrophilic inflammation. This study aimed at determining during early acute lung injury …

Positron emission tomography with [18F]fluorodeoxyglucose to evaluate neutrophil kinetics during acute lung injury

DL Chen, DP Schuster - American Journal of Physiology …, 2004 - journals.physiology.org
We measured neutrophil glucose uptake with positron emission tomographic imaging and
[18F] fluorodeoxyglucose ([18F] FDG-PET) in anesthetized dogs after intravenous oleic acid …

FDG-PET imaging of pulmonary inflammation in healthy volunteers after airway instillation of endotoxin

DL Chen, DB Rosenbluth, MA Mintun… - Journal of Applied …, 2006 - journals.physiology.org
Recent studies indicate that a focal, limited, inflammatory response can be safely elicited
after direct bronchial instillation of small doses of endotoxin into a single lung segment …

[HTML][HTML] Modeling 18F-FDG Kinetics during Acute Lung Injury: Experimental Data and Estimation Errors

AS Dittrich, T Winkler, T Wellman, N de Prost… - PLoS …, 2012 - journals.plos.org
Background There is increasing interest in Positron Emission Tomography (PET) of 2-deoxy-
2-[18F] flouro-D-glucose (18F-FDG) to evaluate pulmonary inflammation during acute lung …

Lungs of patients with acute respiratory distress syndrome show diffuse inflammation in normally aerated regions: a [18F]-fluoro-2-deoxy-D-glucose PET/CT study

G Bellani, C Messa, L Guerra, E Spagnolli… - Critical care …, 2009 - journals.lww.com
Objective: Neutrophilic inflammation plays a key role in the pathogenesis of acute
respiratory distress syndrome (ARDS) and acute lung injury (ALI). Positron emission …