[HTML][HTML] Phylogenetic study of polyketide synthases and nonribosomal peptide synthetases involved in the biosynthesis of mycotoxins
Polyketide synthase (PKSs) and nonribosomal peptide synthetase (NRPSs) are large
multimodular enzymes involved in biosynthesis of polyketide and peptide toxins produced …
multimodular enzymes involved in biosynthesis of polyketide and peptide toxins produced …
Insect-specific polyketide synthases (PKSs), potential PKS-nonribosomal peptide synthetase hybrids, and novel PKS clades in tropical fungi
A Amnuaykanjanasin, S Phonghanpot… - Applied and …, 2009 - Am Soc Microbiol
Polyketides draw much attention because of their potential use in pharmaceutical and
biotechnological applications. This study identifies an abundant pool of polyketide synthase …
biotechnological applications. This study identifies an abundant pool of polyketide synthase …
Multiple hybrid polyketide synthase/non-ribosomal peptide synthetase gene clusters in the myxobacterium Stigmatella aurantiaca
B Silakowski, B Kunze, R Müller - Gene, 2001 - Elsevier
Many bacterial and fungal secondary metabolites are produced by polyketide synthases
(PKS) and non-ribosomal peptide synthetases (NRPS). Recently, it has been discovered …
(PKS) and non-ribosomal peptide synthetases (NRPS). Recently, it has been discovered …
Advances in cloning, functional analysis and heterologous expression of fungal polyketide synthase genes
J Schümann, C Hertweck - Journal of biotechnology, 2006 - Elsevier
Fungal polyketides comprise a diverse group of secondary metabolites that play an
important role for drug discovery, as pigments, and as mycotoxins. Their biosynthesis is …
important role for drug discovery, as pigments, and as mycotoxins. Their biosynthesis is …
[HTML][HTML] Functional analysis of fungal polyketide biosynthesis genes
I Fujii - The Journal of Antibiotics, 2010 - nature.com
Fungal polyketides have huge structural diversity from simple aromatics to highly modified
complex reduced-type compounds. Despite such diversty, single modular iterative type I …
complex reduced-type compounds. Despite such diversty, single modular iterative type I …
Bioactive compounds synthesized by non-ribosomal peptide synthetases and type-I polyketide synthases discovered through genome-mining and metagenomics
K Nikolouli, D Mossialos - Biotechnology letters, 2012 - Springer
Non-ribosomal peptide synthetases (NRPS) and type-I polyketide synthases (PKS-I) are
multimodular enzymes involved in biosynthesis of oligopeptide and polyketide secondary …
multimodular enzymes involved in biosynthesis of oligopeptide and polyketide secondary …
Diversity of polyketide synthase gene sequences in Aspergillus species
Fungal polyketide synthases are responsible for the biosynthesis of several mycotoxins and
other secondary metabolites. The aim of our work was to investigate the diversity of …
other secondary metabolites. The aim of our work was to investigate the diversity of …
Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics
Covering: bacterial genome sequences to 2005 and post-genomic literature to June 2006 A
total of 223 complete bacterial genomes are analyzed, with 281 citations, for the presence of …
total of 223 complete bacterial genomes are analyzed, with 281 citations, for the presence of …
Type III polyketide synthases in natural product biosynthesis
Polyketides represent an important class of biologically active and structurally diverse
compounds in nature. They are synthesized from acyl‐coenzyme A substrates by polyketide …
compounds in nature. They are synthesized from acyl‐coenzyme A substrates by polyketide …
[HTML][HTML] Classification, prediction, and verification of the regioselectivity of fungal polyketide synthase product template domains
The fungal iterative nonreducing polyketide synthases (NRPKSs) synthesize aromatic
polyketides, many of which have important biological activities. The product template …
polyketides, many of which have important biological activities. The product template …