Highlights•Commercial nerve guidance conduits are insufficient to promote enhanced
regeneration.•Multifaceted approaches are needed to mimic native nerve architecture and …

Damage to the peripheral nervous system is surprisingly common and occurs primarily from
trauma or a complication of surgery. Although recovery of nerve function occurs in many mild …

Peripheral nerve injury is a serious health concern for society, affecting 2.8% of trauma
patients, many of whom acquire long-term disability, and the related socioeconomic costs …

A body of evidence indicates that peripheral nerves have an extraordinary yet limited
capacity to regenerate after an injury. Peripheral nerve injuries have confounded …

Despite an intrinsic regenerative capacity of the peripheral nervous system, in most cases of
peripheral nerve injury, especially those involving substantial nerve gaps, therapeutic …

In this chapter, we review several techniques used to repair peripheral nerve injuries and
discuss current limitations that need to be overcome in order to enhance functional recovery …

Peripheral nerve injuries remain a challenging problem in need of better treatment
strategies. Despite best efforts at surgical reconstruction and postoperative rehabilitation …

Peripheral nerve injuries often result in longstanding disability with loss of motor and/or
sensory function. Peripheral nerve tissue engineering researchers have been exploring …

Peripheral nerve injury is a large‐scale problem that annually affects more than several
millions of people all over the world. It remains a great challenge to effectively repair nerve …

Peripheral nerve injury is a common disease that affects more than 20 million people in the
United States alone and remains a major burden to society. The current gold standard …