Disorders of sex development (DSDs) are congenital conditions with discrepancies between
the chromosomal, gonadal, and phenotypic sex of the individual. Such disorders have …

The elegant developmental biology experiments conducted in the 1940s by French
physiologist Alfred Jost demonstrated that the sexual phenotype of a mammalian embryo …

Disorders of sex development (DSD) are congenital conditions in which the development of
chromosomal, gonadal, or anatomical sex is atypical. Many of the genes required for gonad …

Although the genetic basis of human sexual determination and differentiation has advanced
considerably in recent years, the fact remains that in most subjects with disorders of sex …

In this review we will consider the gene mutations responsible for the non-syndromic forms
of disorders of sex development (DSD) and how recent genetic findings are providing …

Disorders of sex development (DSDs) are a diverse group of conditions that can be
challenging to diagnose accurately using standard phenotypic and biochemical …

Disorders of sex development (DSDs) are congenital conditions in which the external
appearance of the individual does not coincide with the chromosomal constitution or the …

The commitment of the embryonic gonad towards the male or female fate is a sequential and
complex developmental process. The sex-independent growth and development of the …

Disorders in human sex determination cause defects in gonadal function and can result in a
spectrum of abnormalities in the internal and external genitalia, ranging from relatively mild …

Disorders (or differences) of sex development (DSD) are a heterogeneous group of
congenital conditions with variations in chromosomal, gonadal, or anatomical sex. Impaired …