Galnon facilitates extinction of morphine-conditioned place preference but also potentiates the consolidation process

X Zhao, K Yun, RR Seese, Z Wang - Plos one, 2013 - journals.plos.org
Learning and memory systems are intimately involved in drug addiction. Previous studies
suggest that galanin, a neuropeptide that binds G-protein coupled receptors, plays essential …

Galanin-3 receptor antagonism by SNAP 37889 reduces motivation to self-administer alcohol and attenuates cue-induced reinstatement of alcohol-seeking in iP rats

BL Ash, T Quach, SJ Williams, AJ Lawrence… - Journal of …, 2014 - jstage.jst.go.jp
The neuropeptide galanin has a role in promoting alcohol consumption and general feeding
behavior. The galanin-3 receptor (GALR3) subtype is implicated in modulating the …

The galanin-3 receptor antagonist, SNAP 37889, suppresses alcohol drinking and morphine self-administration in mice

KJ Scheller, SJ Williams, AJ Lawrence, E Djouma - Neuropharmacology, 2017 - Elsevier
The neuropeptide, galanin, is widely expressed in the central and peripheral nervous
systems and is involved in a range of different functions including nociception …

Galanin negatively modulates opiate withdrawal via galanin receptor 1

FE Holmes, A Armenaki, TP Iismaa, EB Einstein… - …, 2012 - Springer
Rationale The neuropeptide galanin has been shown to modulate opiate dependence and
withdrawal. These effects could be mediated via activation of one or more of the three …

Galanin‐induced decreases in nucleus accumbens/striatum excitatory postsynaptic potentials and morphine conditioned place preference require both galanin …

EB Einstein, Y Asaka, MF Yeckel… - European Journal of …, 2013 - Wiley Online Library
The neuropeptide galanin has been shown to alter the rewarding properties of morphine. To
identify potential cellular mechanisms that might be involved in the ability of galanin to …

Galanin protects against behavioral and neurochemical correlates of opiate reward

JJ Hawes, DH Brunzell, R Narasimhaiah… - …, 2008 - nature.com
The mechanisms underlying responses to drugs of abuse have been widely investigated;
however, less is known about pathways normally protective against the development of drug …

The galanin receptor agonist, galnon, attenuates cocaine‐induced reinstatement and dopamine overflow in the frontal cortex

YE Ogbonmwan, NR Sciolino… - Addiction …, 2015 - Wiley Online Library
Relapse represents one of the most significant problems in the long‐term treatment of drug
addiction. Cocaine blocks plasma membrane monoamine transporters and increases …

[HTML][HTML] Centrally administered galanin blocks morphine place preference in the mouse

V Zachariou, K Parikh, MR Picciotto - Brain research, 1999 - Elsevier
Galanin is a neuropeptide with appetitive, antinociceptive and neuroendocrine functions.
Galanin and galanin binding sites are present in brain areas that mediate reinforcement …

Effects of galanin on cocaine-mediated conditioned place preference and ERK signaling in mice

R Narasimhaiah, HM Kamens, MR Picciotto - Psychopharmacology, 2009 - Springer
Rationale The neuropeptide galanin and its receptors are expressed in brain regions
implicated in the rewarding effects of natural stimuli and drugs of abuse. Galanin has been …

The galanin receptor-3 antagonist, SNAP 37889, inhibits cue-induced reinstatement of alcohol-seeking and increases c-Fos expression in the nucleus accumbens …

KE Wilson, S Limburg, MK Duggan… - Journal of …, 2018 - journals.sagepub.com
Introduction: This study aimed to investigate the effects of the galanin-3 receptor antagonist,
SNAP 37889, on c-Fos protein expression after cue-induced reinstatement of alcohol …