Adiponectin protects from hepatic fat storage but adiponectin deficient mice (APN−/−) fed a
standard chow do not develop liver steatosis. This indicates that other pathways might be …

The effects of adiponectin on hepatic glucose and lipid metabolism at transcriptional level
are largely unknown. We profiled hepatic gene expression in adiponectin knockout (KO) and …

AIM: To determine circulating and hepatic adiponectin in rodents with fatty liver disease or
liver cirrhosis and investigate expression of the adiponectin receptors AdipoR1 on the …

Adiponectin has recently been shown to be a promising candidate for the treatment of
obesity-associated metabolic syndromes. Replenishment of recombinant adiponectin in …

Adiponectin (APN) exerts multiple beneficial effects in obesity and protects from liver injury.
Different APN isoforms circulate in serum, and here, the effect of low molecular weight …

BACKGROUND/AIMS: Models of fatty liver diseases and fibrosis suggest a hepatoprotective
effect of adiponectin, an adipocyte-derived hormone with antidiabetic, antiobesity …

Adiponectin overexpression in mice increases insulin sensitivity independent of adiposity.
Here, we combined stable isotope infusion and in vivo measurements of lipid flux with …

BACKGROUND: Nonalcoholic fatty liver disease is associated with insulin resistance and
low adiponectin levels. Adiponectin circulates as high-, medium-and low-molecular weight …

Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and
metabolic actions. Yamauchi T, Nio Y, Maki T, Kobayashi M, Takazawa T, Iwabu M, Okada …

Nonalcoholic fatty liver disease (NAFLD) is closely associated with obesity. An adipocyte-
derived hormone, adiponectin, may play a role in the pathophysiology of NAFLD through …