Intensive multi‐agent chemotherapy regimens and the introduction of risk‐stratified therapy
have substantially improved cure rates for children with acute lymphoblastic leukaemia …

The single most important prognostic determinant in childhood acute lymphoblastic
leukaemia (ALL) is effective therapy and changes in therapy may influence the significance …

We have reviewed the outcome after relapse in a cohort of 505 children with acute
lymphoblastic leukaemia (ALL) seen at a single institution. The majority of relapses (74%) …

Published studies of the prognostic value of the early response to induction treatment in
childhood acute lymphoblastic leukaemia (ALL) were analysed. Three criteria were used to …

Thirty-two variables at diagnosis of acute lymphoblastic leukaemia (ALL) were studied in an
unselected population-bases series of 209 children. Twelve variables had individually a …

We have examined the toxicity and overall outcome of the Medical Research Council
UKALL R1 protocol for 256 patients with relapsed childhood acute lymphoblastic leukaemia …

Children with acute lymphoblastic leukemia (ALL) and high minimal residual disease (MRD)
levels after initial chemotherapy have a poor clinical outcome. In this prospective, single …

Purpose Improved cure rates for children with acute lymphoblastic leukemia (ALL) have
resulted from better relapse prediction, using clinical and laboratory features at diagnosis …

With current treatment regimens, survival rates for acute lymphoblastic leukemia (ALL) have
improved dramatically since the 1980s, with current 5-year overall survival rates estimated at …

Although most children with acute lymphoblastic leukemia (ALL) are cured, certain subsets
have a high risk of relapse. Relapse risk can be predicted by early response to therapy …