[HTML][HTML] Function of lncRNAs and approaches to lncRNA-protein interactions

JJ Zhu, HJ Fu, YG Wu, XF Zheng - Science China Life Sciences, 2013 - Springer
Long non-coding RNAs (lncRNAs), which represent a new frontier in molecular biology, play
important roles in regulating gene expression at epigenetic, transcriptional and post …

[HTML][HTML] LncRNA structural characteristics in epigenetic regulation

C Wang, L Wang, Y Ding, X Lu, G Zhang… - International Journal of …, 2017 - mdpi.com
The rapid development of new generation sequencing technology has deepened the
understanding of genomes and functional products. RNA-sequencing studies in mammals …

Platforms for investigating LncRNA functions

JL Charles Richard… - … : Translating Life Sciences …, 2018 - journals.sagepub.com
Prior to the sequencing of the human genome, it was presumed that most of the DNA coded
for proteins. However, with the advent of next-generation sequencing, it has now been …

The role of long noncoding RNAs in gene expression regulation

Z Li, W Zhao, M Wang, X Zhou - Gene expression profiling in …, 2019 - books.google.com
Accumulating evidence highlights that noncoding RNAs, especially the long noncoding
RNAs (lncRNAs), are critical regulators of gene expression in development, differentiation …

Revealing lncRNA structures and interactions by sequencing-based approaches

X Qian, J Zhao, PY Yeung, QC Zhang… - Trends in biochemical …, 2019 - cell.com
Long noncoding RNAs (lncRNAs) have emerged as significant players in almost every level
of gene function and regulation. Thus, characterizing the structures and interactions of …

LncRNA-mediated regulation of cell signaling in cancer

WX Peng, P Koirala, YY Mo - Oncogene, 2017 - nature.com
To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …

[HTML][HTML] Molecular mechanisms of long noncoding RNAs and their role in disease pathogenesis

G Hu, F Niu, BA Humburg, K Liao, S Bendi, S Callen… - Oncotarget, 2018 - ncbi.nlm.nih.gov
LncRNAs are long non-coding regulatory RNAs that are longer than 200 nucleotides. One of
the major functions of lncRNAs is the regulation of specific gene expression at multiple steps …

[HTML][HTML] Regulatory long non-coding RNA and its functions

Y Huang, N Liu, JP Wang, YQ Wang, XL Yu… - Journal of physiology …, 2012 - Springer
The discovery of large numbers of long non-coding RNAs (lncRNAs) has been driven by
genome-wide transcriptional analyses. Compared to small ncRNAs, lncRNAs have been …

Regulation of lncRNA expression

Z Wu, X Liu, L Liu, H Deng, J Zhang, Q Xu… - Cellular & molecular …, 2014 - Springer
Long non-coding RNAs (lncRNAs) are series of transcripts with important biological
functions. Various diseases have been associated with aberrant expression of lncRNAs and …

Long noncoding RNAs: regulation, function and cancer

A Rafiee, F Riazi-Rad, M Havaskary… - … and Genetic Engineering …, 2018 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are non-protein-coding RNA transcripts that exert a key
role in many cellular processes and have potential toward addressing disease etiology …