Several endocrine‐disrupting chemicals with estrogenic activity can affect sexual
development and reproduction in aquatic wildlife. The occurrence of oocytes in the testis …

The usefulness of Xenopus tropicalis as a model species to investigate endocrine disruption
and developmental reproductive toxicity was assessed. In our test system tadpoles were …

Reproductive disorders in wildlife and humans have been linked to developmental exposure
to endocrine disrupting chemicals. In frog tadpoles, environmental concentrations of …

Exposure of amphibians to endocrine disrupting compounds (EDCs) may alter
differentiationof gonads, especially when exposures begin during early life stages. Gonadal …

It is known that estrogen-like environmental pollutants can feminise gonadal differentiation
in frogs resulting in female-biased sex-ratios at metamorphosis. The long-term effects on …

Populations of amphibians are in decline in certain locations around the world, and the
possible contribution of environmental contaminants, including estrogenic compounds, to …

Although the past two decades have witnessed a significant increase in the number of
studies investigating effects of estrogenic chemicals on amphibians, to date little is known …

Extensive studies have shown that estrogenic endocrine-disrupting chemicals (EDCs) can
disrupt testis differentiation and even cause feminization in vertebrates. However, little is …

Exposure to estrogens during the period of sexual differentiation is known to adversely affect
the development of testes in African clawed frogs (Xenopus laevis), but little is known about …

Xenopus laevis is an important model for detecting feminizing effects of endocrine disrupting
chemicals (EDCs) on amphibians because its genetic males can be induced to phenotypic …