The skeleton serves as the principal site for hematopoiesis in adult terrestrial vertebrates.
The function of the hematopoietic system is to maintain homeostatic levels of all circulating …

Chemotactic factors direct the migration of immune cells, multipotent stem cells, and
progenitor cells under physiologic and pathologic conditions. Chemokine ligand 12 and …

Progressive fibrosis is a pathological hallmark of many chronic diseases responsible for
organ failure. Although there is currently no therapy on the market that specifically targets …

Background—We investigated the effects of transendocardial CD34+ cell transplantation in
patients with ischemic cardiomyopathy. Methods and Results—In a prospective crossover …

Introduction: A common feature of many types of cells is their responsiveness to chemotactic
gradients of factors for which they express the corresponding receptors. The most studied …

Glioblastoma recurrence involves the persistence of a subpopulation of cells with enhanced
tumor-initiating capacity (TIC) that reside within the perivascular space, or niche (PVN). Anti …

Background Mesenchymal stromal cells (MSC) can be obtained from potentially any tissue
from the human body, but cells purified from different sources are undoubtedly different, and …

Leukocyte cell-derived chemotaxin 2 (LECT2) is reported to be a cytokine involved in the
immune response against pathogenic microorganisms in fish. However, its accurate function …

Hematopoiesis in vertebrates is sustained over the duration of an organism's lifetime due to
strict regulation of the highly hierarchical hematopoietic system, where a few immature …

IL-33 has been implicated in the pathogenesis of asthma, atopic allergy, anaphylaxis, and
other inflammatory diseases by promoting the production of proinflammatory cytokines and …