Hapten‐induced contact hypersensitivity, autoimmune reactions, and tumor regression: plausibility of mediating antitumor immunity

DA Erkes, SR Selvan - Journal of immunology research, 2014 - Wiley Online Library
Haptens are small molecule irritants that bind to proteins and elicit an immune response.
Haptens have been commonly used to study allergic contact dermatitis (ACD) using animal …

Enhancement of Angiogenesis and Epithelialization Processes in Mice with Burn Wounds through ROS/RNS Signals Generated by Non‐Thermal N2/Ar Micro …

MH Ngo Thi, PL Shao, JD Liao… - Plasma Processes and …, 2014 - Wiley Online Library
Non‐thermal 0.5% N2/Ar micro‐plasma treatment with relatively high NO content was
conducted on mice with second‐degree burn wounds. Reactive oxygen species (ROS) and …

Long term effect of curcumin in regulation of glycolytic pathway and angiogenesis via modulation of stress activated genes in prevention of cancer

L Das, M Vinayak - PloS one, 2014 - journals.plos.org
Oxidative stress, an important factor in modulation of glycolytic pathway and induction of
stress activated genes, is further augmented due to reduced antioxidant defense system …

Redox regulation of endothelial cell fate

P Song, MH Zou - Cellular and molecular life sciences, 2014 - Springer
Endothelial cells (ECs) are present throughout blood vessels and have variable roles in both
physiological and pathological settings. EC fate is altered and regulated by several key …

Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival

JM Funes, S Henderson, R Kaufman, JM Flanagan… - Molecular cancer, 2014 - Springer
Abstract Background The transcription factor Nrf2 is a key regulator of the cellular
antioxidant response, and its activation by chemoprotective agents has been proposed as a …

Wogonin inhibits H2O2-induced angiogenesis via suppressing PI3K/Akt/NF-κB signaling pathway

M Zhou, X Song, Y Huang, L Wei, Z Li, Q You… - Vascular …, 2014 - Elsevier
Wogonin, a natural monoflavonoid extracted from Scutellariae radix, has been reported for
its ability of inhibiting tumor angiogenesis. In this study, we assessed the effect of wogonin …

[HTML][HTML] Rotenone induces neurotoxicity through Rac1-dependent activation of NADPH oxidase in SHSY-5Y cells

R Pal, TO Monroe, M Palmieri, M Sardiello, GG Rodney - FEBS letters, 2014 - Elsevier
Neurodegenerative diseases are attributed to impairment of the ubiquitin–proteasome
system (UPS). Oxidative stress has been considered a contributing factor in the pathology of …

Genetic interactions of STAT3 and anticancer drug development

B Fang - Cancers, 2014 - mdpi.com
Signal transducer and activator of transcription 3 (STAT3) plays critical roles in
tumorigenesis and malignant evolution and has been intensively studied as a therapeutic …

The emergence of the mitochondrial genome as a partial regulator of nuclear function is providing new insights into the genetic mechanisms underlying age-related …

MP Horan, DN Cooper - Human genetics, 2014 - Springer
Mitochondrial malfunction appears to be intimately associated with age and age-related
complex disorders but the precise pathological relevance of such malfunction remains …

Inhibition of cellular proliferation and enhancement of hydrogen peroxide production in fibrosarcoma cell line by weak radio frequency magnetic fields

PR Castello, I Hill, F Sivo, L Portelli… - …, 2014 - Wiley Online Library
This study presents experimental data for the effects of weak radio frequency (RF) magnetic
fields on hydrogen peroxide (H2O2) production and cellular growth rates of fibrosarcoma …