Radioresistance remains a significant therapeutic obstacle in glioblastoma. Reactive oxygen
species (ROS) are associated with multiple cellular functions such as cell proliferation and …

Background Snail transcription factor can induce epithelial-mesenchymal transition (EMT),
associated with decreased cell adhesion-associated molecules like E-cadherin, increased …

The objectives of this study were to evaluate the in vitro and in vivo anti-tumor potential of
the aqueous gall extract (G extract) from Limoniastrum guyonianum and to elucidate its …

Induction of excessive levels of reactive oxygen species (ROS) by small-molecule
compounds has been considered a potentially effective therapeutic strategy against cancer …

Tumor growth depends on angiogenesis, which can furnish the oxygen and nutrients that
proliferate tumor cells. Thus, blocking angiogenesis can be an effective strategy to inhibit …

A novel copper (II) complex with mixed ligands including β‐[(3‐formyl‐5‐methyl‐2‐hydroxy‐
benzylidene) amino] propionic acid anion and 1, 10′‐phenanthroline was synthesized, and …

自由基是带有一个孤对电子的分子, 具有很强的反应性. 自由基可以直接与细胞组成成分发生
反应, 造成细胞损伤, 如通过氧化线粒体DNA 和线粒体心磷脂对线粒体造成氧化损伤 …

Expression of vascular endothelial growth factor, major endothelial specific glycoprotein
growth factor that promotes angiogenesis is regulated at transcriptional, post transcriptional …

The large majority of clinical prostate cancers remain dependent on androgen receptor (AR)
activity for proliferation even as they lose their responsiveness to androgen deprivation or …

The adult kidney is derived from the interaction between the metanephric blastema and the
ureteric bud. Platelet-derived growth factor (PDGF) receptor β is essential for the …