Objective. Spatial localization of neural activity from within the brain with
electrocorticography (ECoG) and electroencephalography remains a challenge in clinical …

Mammalian neural circuits are sophisticated biological systems that choreograph behavioral
processes vital for survival. While the inherent complexity of discrete neural circuits has …

It is well established that neural circuits consist of a great diversity of cell types, but very little
is known about how neuronal diversity contributes to cognition and behavior. One approach …

Understanding the function and organization of billions of neurons and trillions of connecting
synapses in the human brain is a tremendous challenge requiring coordinated efforts from …

We establish performance characteristics of needle-type waveguides in three-dimensional
array architectures as light delivery interfaces into deep tissue for applications, such as …

Background The advent of optogenetics has given neuroscientists the opportunity to excite
or inhibit neuronal population activity with high temporal resolution and cellular selectivity …

The firing patterns of cerebellar Purkinje cells (PCs), as the sole output of the cerebellar
cortex, determine and tune motor behavior. PC firing is modulated by various inputs from …

Recent technological advances open exciting avenues for improving the understanding of
mechanisms in a broad range of epilepsies. This chapter focuses on the development of …

The mouse is essential for genetic studies of motor function in both normal and pathological
states. Thus it is important to consider whether the structure of motor output from the mouse …

Molecular manipulations and targeted pharmacological studies provide a compelling picture
of which nicotinic receptor subtypes are where in the central nervous system (CNS) and …