The Role of Antifungals against Candida Biofilm in Catheter-Related Candidemia

E Bouza, J Guinea, M Guembe - Antibiotics, 2014 - mdpi.com
Catheter-related bloodstream infection (C-RBSI) is one of the most frequent nosocomial
infections. It is associated with high rates of morbidity and mortality. Candida spp. is the third …

Polymer multilayers loaded with antifungal β-peptides kill planktonic Candida albicans and reduce formation of fungal biofilms on the surfaces of flexible catheter …

N Raman, MR Lee, SP Palecek, DM Lynn - Journal of Controlled Release, 2014 - Elsevier
Candida albicans is the most common fungal pathogen responsible for hospital-acquired
infections. Most C. albicans infections are associated with the implantation of medical …

Saccharomyces cerevisiae biofilm tolerance towards systemic antifungals depends on growth phase

R Bojsen, B Regenberg, A Folkesson - BMC microbiology, 2014 - Springer
Abstract Background Biofilm-forming Candida species cause infections that can be difficult
to eradicate, possibly because of antifungal drug tolerance mechanisms specific to biofilms …

A Novel Antifungal Is Active against Candida albicans Biofilms and Inhibits Mutagenic Acetaldehyde Production In Vitro

MT Nieminen, L Novak-Frazer, V Rautemaa… - Plos one, 2014 - journals.plos.org
The ability of C. albicans to form biofilms is a major virulence factor and a challenge for
management. This is evident in biofilm-associated chronic oral-oesophageal candidosis …

Anti-Candida albicans biofilm effect of novel heterocyclic compounds

S Kagan, A Jabbour, E Sionov… - Journal of …, 2014 - academic.oup.com
Objectives The aims of this study were to develop new anti-biofilm drugs, examine their
activity against Candida albicans biofilm and investigate their structure–activity relationship …

Progress and prospects for targeting Hsp90 to treat fungal infections

A Veri, LE Cowen - Parasitology, 2014 - cambridge.org
Fungal pathogens pose a major threat to human health worldwide. They infect billions of
people each year, leading to at least 1· 5 million deaths. Treatment of fungal infections is …

[PDF][PDF] Miconazole activity against Candida biofilms developed on acrylic discs

S Gebremedhin, B Dorocka-Bobkowska… - J Physiol …, 2014 - jpp.krakow.pl
Oral candidiasis in the form of Candida-associated denture stomatitis (CaDS) is associated
with Candida adhesion and biofilm formation on the fitting surface of poly (methyl …

Antifungal activity of endosequence root repair material and mineral trioxide aggregate

F Alsalleeh, N Chung, L Stephenson - Journal of endodontics, 2014 - Elsevier
Introduction The purpose of this study was to investigate the antifungal activity of
Endosequence Root Repair Material (ERRM; Brasseler USA, Savannah, GA) as compared …

Quinacrine inhibits Candida albicans growth and filamentation at neutral pH

VV Kulkarny, A Chavez-Dozal, HS Rane… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Candida albicans is a common cause of catheter-related bloodstream infections (CR-BSI), in
part due to its strong propensity to form biofilms. Drug repurposing is an approach that might …

Fungal biofilms in human disease

C Williams, G Ramage - Biofilm-based Healthcare-associated Infections …, 2014 - Springer
Fungal biofilms are an important clinical problem. A number of factors including the
increasing use of indwelling medical devices wider prescription of broad spectrum …