Retrotransposition of long interspersed element 1 induced by methamphetamine or cocaine

N Okudaira, Y Ishizaka, H Nishio - Journal of Biological Chemistry, 2014 - ASBMB
Long interspersed element 1 (L1) is a retroelement constituting∼ 17% of the human
genome. A single human cell has 80–100 copies of L1 capable of retrotransposition (L1 …

Reading LINE s within the cocaine addicted brain

GA Doyle, TT DoucetO'Hare, MJ Hammond… - Brain and …, 2017 - Wiley Online Library
Introduction Long interspersed element (LINE)1 (L1) is a type of retrotransposon capable of
mobilizing into new genomic locations. Often studied in Mendelian diseases or cancer, L1s …

Induction of long interspersed nucleotide element-1 (L1) retrotransposition by 6-formylindolo[3,2-b]carbazole (FICZ), a tryptophan photoproduct

N Okudaira, K Iijima, T Koyama… - Proceedings of the …, 2010 - National Acad Sciences
Long interspersed nucleotide element-1 (L1) is a retroelement comprising about 17% of the
human genome, of which 80–100 copies are competent as mobile elements …

Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans

M Sokolowski, M Chynces, D DeHaro… - Nucleic acids …, 2017 - academic.oup.com
Abstract Long interspersed element 1 (L1) is an autonomous non-LTR retroelement that is
active in mammalian genomes. Although retrotranspositionally incompetent and functional …

Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p in different anatomical regions of the human brain

D Sur, RK Kustwar, S Budania, A Mahadevan… - Mobile DNA, 2017 - Springer
Background Recent reports indicate that retrotransposons–a type of mobile DNA–can
contribute to neuronal genetic diversity in mammals. Retrotransposons are genetic elements …

Inhibition of LINE-1 retrotransposition by capsaicin

Y Nishikawa, R Nakayama, S Obika, E Ohsaki… - International journal of …, 2018 - mdpi.com
Long interspersed nuclear element 1 (LINE-1 or L1) is a non-long terminal repeat (LTR)
retrotransposon that constitutes approximately 17% of the human genome. Since …

Modes of retrotransposition of long interspersed element-1 by environmental factors

Y Ishizaka, N Okudaira, M Tamura, K Iijima… - Frontiers in …, 2012 - frontiersin.org
Approximately 42% of the human genome is composed of endogenous retroelements, and
the major retroelement component, long interspersed element-1 (L1), comprises∼ 17% of …

A potential role for RNA interference in controlling the activity of the human LINE-1 retrotransposon

HS Soifer, A Zaragoza, M Peyvan… - Nucleic acids …, 2005 - academic.oup.com
Long interspersed nuclear elements (LINE-1 or L1) comprise 17% of the human genome,
although only 80–100 L1s are considered retrotransposition-competent (RC-L1). Despite …

Cell division promotes efficient retrotransposition in a stable L1 reporter cell line

Y Xie, L Mates, Z Ivics, Z Izsvák, SL Martin, W An - Mobile DNA, 2013 - Springer
Background Long interspersed element type one (L1) actively modifies the human genome
by inserting new copies of itself. This process, termed retrotransposition, requires the …

L1 retrotransposition in neural progenitor cells

AR Muotri - Transposons and Retrotransposons: Methods and …, 2016 - Springer
Long interspersed nucleotide element 1 (LINE-1 or L1) is a family of non-LTR
retrotransposons that can replicate and reintegrate into the host genome. L1s have …