Syncope in genotype-negative long QT syndrome family members

LRAO Nordkamp, MH Ruwald, I Goldenberg… - The American Journal of …, 2014 - Elsevier
Unaffected long-QT syndrome family members (FMs) frequently experience syncope. The
aims of this study were to test the hypothesis that syncope events in FMs are benign events …

Risk of syncope in family members who are genotype-negative for a family-associated long-QT syndrome mutation

A Barsheshet, AJ Moss, S McNitt… - Circulation …, 2011 - Am Heart Assoc
Background—Current clinical diagnosis of long-QT syndrome (LQTS) includes genetic
testing of family members of mutation-positive patients. The present study was designed to …

Risk factors for recurrent syncope and subsequent fatal or near-fatal events in children and adolescents with long QT syndrome

JF Liu, C Jons, AJ Moss, S McNitt, DR Peterson… - Journal of the American …, 2011 - jacc.org
Objectives: We aimed to identify risk factors for recurrent syncope in children and
adolescents with congenital long QT syndrome (LQTS). Background: Data regarding risk …

Association between syncope trigger type and risk of subsequent life-threatening events in patients with long QT syndrome

A Younis, JM Bos, W Zareba, MK Aktas… - JAMA …, 2023 - jamanetwork.com
Importance Syncope is the most powerful predictor for subsequent life-threatening events
(LTEs) in patients with congenital long QT syndrome (LQTS). Whether distinct syncope …

Phenotypes of overdiagnosed long QT syndrome

S Bains, R Neves, JM Bos, JR Giudicessi… - Journal of the American …, 2023 - jacc.org
Abstract Background Long QT syndrome (LQTS) predisposes individuals to arrhythmic
syncope or seizure, sudden cardiac arrest, or sudden cardiac death (SCD). Increased …

Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval

J Ghouse, CT Have, P Weeke… - European heart …, 2015 - academic.oup.com
Aims We studied whether variants previously associated with congenital long QT syndrome
(cLQTS) have an effect on the QTc interval in a Danish population sample. Furthermore, we …

Vasovagal syncope as a cause of syncope in long-QT syndrome

LRA Olde Nordkamp, W Wieling, N van Dijk - Journal of the American …, 2011 - jacc.org
The report by Liu et al.(1) containing data from the International Long QT Syndrome Registry
regarding the risk factors for recurrent syncope and subsequent fatal or near fatal events in …

Value of history-taking in syncope patients: in whom to suspect long QT syndrome?

N Colman, A Bakker, M Linzer, JB Reitsma… - Europace, 2009 - academic.oup.com
Abstract Aims Long QT syndrome (LQTS), a potentially fatal disorder, has to be
distinguished from non-fatal conditions. Our aim was to investigate whether history-taking …

Long QT syndrome patients may faint due to neurocardiogenic syncope

E Toft, J Aarøe, BT Jensen, M Christiansen, L Fog… - EP …, 2003 - academic.oup.com
Aims Syncope in long QT syndrome (LQTS) is expected to be due to Torsades de Pointes
ventricular tachycardia (TdP). Often these patients faint in situations with emotional stress …

Long QT syndrome patients with gene mutations

MR Rosen - Circulation, 1995 - Am Heart Assoc
In their article in this issue of Circulation, Schwartz and colleagues 1 deliver not only an
important message in the rapidly advancing field of long QT syndrome but an equally …