The role of heat shock proteins in atherosclerosis

G Wick, B Jakic, M Buszko, MC Wick… - Nature Reviews …, 2014 - nature.com
Atherosclerosis is a chronic, multifactorial disease that starts in youth, manifests clinically
later in life, and can lead to myocardial infarction, stroke, claudication, and death. Although …

The role of heat shock protein (HSP) in atherosclerosis: Pathophysiology and clinical opportunities

X Lu, V Kakkar - Current medicinal chemistry, 2010 - ingentaconnect.com
The highly conserved heat-shock proteins (HSPs) from mammals and microbial reagents
are among the immunogenic proteins. Their expression is induced in response to a wide …

Molecular chaperones and heat shock proteins in atherosclerosis

Q Xu, B Metzler, M Jahangiri… - American Journal of …, 2012 - journals.physiology.org
In response to stress stimuli, mammalian cells activate an ancient signaling pathway leading
to the transient expression of heat shock proteins (HSPs). HSPs are a family of proteins …

[HTML][HTML] Tolerization against atherosclerosis using heat shock protein 60

C Wick - Cell Stress and Chaperones, 2016 - Elsevier
Atherosclerosis is a chronic inflammatory disease of the artery wall, and both innate and
adaptive immunity play important roles in the pathogenesis of this disease. In several …

Heat shock proteins and autoimmunity in patients with carotid atherosclerosis

R Riganò, E Profumo, B Buttari… - Annals of the New …, 2007 - Wiley Online Library
Studies aimed at elucidating the pathogenetic mechanisms underlying the initiation and
progression of human atherosclerosis have emphasized the central role of inflammatory and …

Heat-shock proteins in cardiovascular disease

J Madrigal-Matute, JL Martin-Ventura… - Advances in clinical …, 2011 - Elsevier
Heat-shock proteins (HSPs) belong to a group of highly conserved families of proteins
expressed by all cells and organisms and their expression may be constitutive or inducible …

Infections, heat shock proteins, and atherosclerosis

Q Xu - Current Opinion in Cardiology, 2003 - journals.lww.com
Recent evidence indicates that infections or a pathogen burden contribute to the
development and progression of atherosclerosis. While the mechanism of infection …

Heat shock proteins: pathogenic role in atherosclerosis and potential therapeutic implications

A Kilic, K Mandal - Autoimmune diseases, 2012 - Wiley Online Library
Heat shock proteins (HSPs) are a highly conserved group of proteins that are constitutively
expressed and function as molecular chaperones, aiding in protein folding and preventing …

Heat shock protein 60 and immune inflammatory responses in atherosclerosis

C Grundtman, SB Kreutmayer, G Almanzar… - … , and vascular biology, 2011 - Am Heart Assoc
Hallmarks of inflammation in various cardiovascular diseases, notably atherosclerosis, have
been observed for a long time. However, evidence for an (auto) antigen-driven process at …

Role of heat shock proteins in atherosclerosis

Q Xu - Arteriosclerosis, thrombosis, and vascular biology, 2002 - Am Heart Assoc
Heat shock proteins (HSPs) are present in most cells, serving as molecular chaperones, and
they play a role in cell protection from damage in response to stress stimuli. However …