Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies

K Sharma, DA Kass - Circulation research, 2014 - Am Heart Assoc
The clinical syndrome comprising heart failure (HF) symptoms but with a left ventricular
ejection fraction (EF) that is not diminished, eg, HF with preserved EF, is increasingly the …

Heart failure with preserved ejection fraction

JD Gladden, AH Chaanine… - Annual review of …, 2018 - annualreviews.org
Heart failure (HF) is a clinical syndrome of diverse etiologies and can be associated with
preserved, reduced, or mid-range ejection fraction (EF). In the community, heart failure with …

Heart failure with preserved ejection fraction

JD Gladden, WA Linke, MM Redfield - Pflügers Archiv-European Journal …, 2014 - Springer
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Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management

AB Gevaert, R Kataria, F Zannad, AJ Sauer, K Damman… - Heart, 2022 - heart.bmj.com
It is estimated that half of all patients with heart failure (HF) have HF with preserved ejection
fraction (HFpEF). Yet this form of HF remains a diagnostic and therapeutic challenge …

The pathophysiology of heart failure with preserved ejection fraction

BA Borlaug - Nature Reviews Cardiology, 2014 - nature.com
Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …

Heart failure with preserved ejection fraction in perspective

MA Pfeffer, AM Shah, BA Borlaug - Circulation research, 2019 - Am Heart Assoc
Approximately half of the patients with signs and symptoms of heart failure have a left
ventricular ejection fraction that is not markedly abnormal. Despite the historically initial …

Research priorities for heart failure with preserved ejection fraction: national heart, lung, and blood institute working group summary

SJ Shah, BA Borlaug, DW Kitzman, AD McCulloch… - Circulation, 2020 - Am Heart Assoc
Heart failure with preserved ejection fraction (HFpEF), a major public health problem that is
rising in prevalence, is associated with high morbidity and mortality and is considered to be …

Heart failure with preserved ejection fraction

YNV Reddy, BA Borlaug - Current problems in cardiology, 2016 - Elsevier
Heart failure (HF) is one of the largest drivers of morbidity and health care expenditure in the
world and continues to increase in prevalence at an alarming rate. Most of this increasing …

Heart failure with preserved ejection fraction: current understandings and challenges

MJ Andersen, BA Borlaug - Current cardiology reports, 2014 - Springer
Heart failure (HF) is the leading cause of hospitalization among older adults and the
prevalence is growing with the aging populations in western countries. Approximately one …

The many faces of heart failure with preserved ejection fraction

AM Shah, MA Pfeffer - Nature Reviews Cardiology, 2012 - nature.com
By definition, patients with heart failure and preserved ejection fraction are characterized by
a normal or near-normal left ventricular ejection fraction, but marked heterogeneity in the …