Cancer cells are characterized by an increase in the rate of reactive oxygen species (ROS)
production and an altered redox environment compared to normal cells. Furthermore, redox …

The regulation of oxidative stress is an important factor in both tumour development and
responses to anticancer therapies. Many signalling pathways that are linked to …

Increased generation of reactive oxygen species (ROS) and an altered redox status have
long been observed in cancer cells, and recent studies suggest that this biochemical …

Redox homeostasis is essential for the maintenance of diverse cellular processes. Cancer
cells have higher levels of reactive oxygen species (ROS) than normal cells as a result of …

Reactive oxygen species (ROS) are a group of highly reactive chemicals under tight control
of intracellular antioxidants. The balance in oxidation-antioxidation is essential for …

Reactive oxygen species (ROS) and their products are components of cell signaling
pathways and play important roles in cellular physiology and pathophysiology. Under …

The vulnerability of some cancer cells to oxidative signals is a therapeutic target for the
rational design of new anticancer agents. In addition to their well characterized effects on …

Significance: Cancer cells that are resistant to radiation and chemotherapy are a major
problem limiting the success of cancer therapy. Aggressive cancer cells depend on elevated …

The role of reactive oxygen species (ROS) in cancer cells has been intensively studied for
the past two decades. Cancer cells mostly have higher basal ROS levels than their normal …

The cellular REDOX regulatory systems play a central role in maintaining REDOX
homeostasis that is crucial for cell integrity, survival, and proliferation. To date, a substantial …