Abstract Background Human Immunodeficiency Virus (HIV) and Schistosomiasis co-
infection is common among residents at the shores of Lake Victoria in Kenya. About 36% of …

Background Chronic schistosomiasis is predominantly induced through up-regulation of
inflammatory cytokines such as interleukin (IL)-13. IL-13 may contribute to the disease …

Background Schistosomiasis remains a major public health issue with over 90% of the
prevalence rates recorded in Sub-Saharan Africa. In this study, the relationships between …

Background IL-13 is a signature cytokine of the helper T cell type 2 (TH2) pathway which
underlies host defense to helminthic infection and activates production of IgE in both …

The aim of this study was to determine whether two polymorphisms in the gene encoding
IL13 previously associated with Schistosoma hematobium (S. hematobium) and S. mansoni …

Malaria infection is a multifactorial disease partly modulated by host immuno-genetic factors.
Recent evidence has demonstrated the importance of Interleukin-17 family proinflammatory …

Background: This study aimed to investigate the association of plasma levels of IL-33, a
mucosal alarmin known to elicit type-2 immunity, with infection and liver fibrosis profiles of …

Schistosomiasis is endemic in many parts of rural Africa, with previous reports showing
interleukin-13 polymorphisms as drivers of infectivity and disease severity in West Africa …

Background Improved understanding of the molecular mechanisms involved in pediatric
severe malarial anemia (SMA) pathogenesis is a crucial step in the design of novel …

Background Emerging evidence suggests that the interleukin (IL) 17/IL-23 axis may play a
role in the pathogenesis of leishmaniasis. Our aim was to investigate whether the IL-23R …