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Lipid nanoparticles (LNPs) are currently the most promising clinical nucleic acids drug
delivery vehicles. LNPs prevent the degradation of cargo nucleic acids during blood …

DNA vaccination has been extensively studied as a promising strategy for tumor treatment.
Despite the efforts, the therapeutic efficacy of DNA vaccines has been limited by their …

Lipid nanoparticles hold great potential as an effective non-viral vector for nucleic acid-
based gene therapy. Plasmid DNA delivery can result in extended transgene expression …

Ionizable cationic lipids play a critical role in developing new gene therapies for various
biomedical applications, including COVID-19 vaccines. However, it remains unclear whether …

Lipid nanoparticle (LNP)-based drug delivery systems have become the most clinically
advanced non-viral delivery technology. LNPs can encapsulate and deliver a wide variety of …

Lipid nanoparticles (LNPs) have recently risen to prominence as the technology platform
that enables the delivery of mRNA, the key component of the Moderna and BioNTech/Pfizer …

Lipid nanoparticles (LNPs) containing distearoylphosphatidlycholine (DSPC), and ionizable
amino-lipids such as dilinoleylmethyl-4-dimethylaminobutyrate (DLin-MC3-DMA) are potent …

Lipid nanoparticles (LNPs) have shown remarkable success in delivering genetic materials
like COVID-19 LNP vaccines, such as mRNA-1273/SpikeVax by Moderna and …