Igniting thermogenesis within white adipose tissue (ie, promoting expression and activity of
the uncoupling protein UCP1) has attracted much interest. Numerous" browning agents" …

The possibility that brown adipose tissue thermogenesis can be recruited in order to combat
the development of obesity has led to a high interest in the identification of “browning …

Uncoupling protein 1 (Ucp1) is the key component of β-adrenergically controlled
nonshivering thermogenesis in brown adipocytes. This process combusts stored and …

To examine the thermogenic significance of the classical uncoupling protein-1 (UCP1), the
thermogenic potential of brown adipocytes isolated from UCP1-ablated mice was …

The growing focus on brown adipocytes has spurred an interest in their potential benefits for
metabolic diseases. Brown and beige (or brite) adipocytes express high levels of uncoupling …

Because of the possible role of brown adipose tissue and UCP1 in metabolic regulation,
even in adult humans, there is presently considerable interest in quantifying, from in-vitro …

Energy expenditure through brown adipose tissue thermogenesis contributes either to
maintenance of body temperature in a cold environment or to wasted food energy, ie cold …

Apart from UCP1-based nonshivering thermogenesis in brown adipocytes, the identity of
thermogenic mechanisms that can be activated to reduce a positive energy balance is …

The phenomenon of white fat" browning," in which certain white adipose tissue depots
significantly increase gene expression for the uncoupling protein UCP1 and thus …

Energy balance to prevent the development of obesity is dependent on energy expenditure.
Although physical activity is the dominant mechanism for dissipating excess energy, a …