Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia
KG Roberts, Y Li, D Payne-Turner… - New England journal …, 2014 - Mass Medical Soc
Background Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …
Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group
SC Reshmi, RC Harvey, KG Roberts… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome-like (Ph-like) acute lymphoblastic leukemia (ALL) is a high-risk
subtype characterized by genomic alterations that activate cytokine receptor and kinase …
subtype characterized by genomic alterations that activate cytokine receptor and kinase …
Ph-like acute lymphoblastic leukemia
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is a newly
identified high-risk (HR) B-lineage ALL subtype, accounting for∼ 15% of children with …
identified high-risk (HR) B-lineage ALL subtype, accounting for∼ 15% of children with …
Genomic and outcome analyses of Ph-like ALL in NCI standard-risk patients: a report from the Children's Oncology Group
KG Roberts, SC Reshmi, RC Harvey… - Blood, The Journal …, 2018 - ashpublications.org
Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL; BCR-ABL1–like
ALL) in children with National Cancer Institute (NCI) intermediate-or high-risk (HR) ALL is …
ALL) in children with National Cancer Institute (NCI) intermediate-or high-risk (HR) ALL is …
High frequency and poor outcome of Philadelphia chromosome–like acute lymphoblastic leukemia in adults
KG Roberts, Z Gu, D Payne-Turner… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a high-
risk subtype of childhood ALL characterized by kinase-activating alterations that are …
risk subtype of childhood ALL characterized by kinase-activating alterations that are …
Philadelphia chromosome–like acute lymphoblastic leukemia
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL), also referred to as
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …
BCR-ABL1–like ALL, is a high-risk subset with a gene expression profile that shares …
Oncogenic role and therapeutic targeting of ABL-class and JAK-STAT activating kinase alterations in Ph-like ALL
KG Roberts, YL Yang, D Payne-Turner, W Lin… - Blood …, 2017 - ashpublications.org
New therapies for Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like
ALL) patients are urgently needed. The genetic landscape of Ph-like ALL is characterized by …
ALL) patients are urgently needed. The genetic landscape of Ph-like ALL is characterized by …
[HTML][HTML] Development and validation of a highly sensitive and specific gene expression classifier to prospectively screen and identify B-precursor acute lymphoblastic …
RC Harvey, H Kang, KG Roberts, IML Chen, SR Atlas… - Blood, 2013 - Elsevier
Using gene expression profiling, we and others identified a novel subgroup of B-precursor
acute lymphoblastic leukemia (B-ALL) with a gene expression signature similar to …
acute lymphoblastic leukemia (B-ALL) with a gene expression signature similar to …
Clinical diagnostics and treatment strategies for Philadelphia chromosome–like acute lymphoblastic leukemia
RC Harvey, SK Tasian - Blood advances, 2020 - ashpublications.org
Philadelphia chromosome-like B-cell acute lymphoblastic leukemia (Ph-like ALL) accounts
for 15% to 30% of B-cell acute lymphoblastic leukemia in older children, adolescents, and …
for 15% to 30% of B-cell acute lymphoblastic leukemia in older children, adolescents, and …
Genomics in acute lymphoblastic leukaemia: insights and treatment implications
KG Roberts, CG Mullighan - Nature reviews Clinical oncology, 2015 - nature.com
Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer and an important
cause of morbidity from haematological malignancies in adults. In the past several years, we …
cause of morbidity from haematological malignancies in adults. In the past several years, we …