[HTML][HTML] MicroRNAs in heart failure: Small molecules with major impact

G Kalozoumi, M Yacoub, D Sanoudou - Global Cardiology Science …, 2014 - qscience.com
MicroRNAs (miRNAs) have emerged as potent modulators of mammalian gene expression,
thereby broadening the spectrum of molecular mechanisms orchestrating human …

MicroRNAs in heart failure: new targets in disease management

I Elzenaar, YM Pinto, RJ Van Oort - Clinical Pharmacology & …, 2013 - Wiley Online Library
Heart failure is the leading cause of mortality in Western society and represents the fastest
growing subclass of cardiovascular diseases. An increasing body of evidence indicates an …

MicroRNAs in heart failure: is the picture becoming less miRky?

YF Melman, R Shah, S Das - Circulation: Heart Failure, 2014 - Am Heart Assoc
204 Circ Heart Fail January 2014 family regulating multiple components of pathways. A
single miRNA may have tens to hundreds of targets in a given cell, and an individual mRNA …

[HTML][HTML] MicroRNA and heart failure

LL Wong, J Wang, OW Liew, AM Richards… - International journal of …, 2016 - mdpi.com
Heart failure (HF) imposes significant economic and public health burdens upon modern
society. It is known that disturbances in neurohormonal status play an important role in the …

MicroRNAs in heart failure: from biomarker to target for therapy

EL Vegter, P van der Meer, LJ de Windt… - European journal of …, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are increasingly recognized to play important roles in cardiovascular
diseases, including heart failure. These small, non‐coding RNAs have been identified in …

Role of microRNAs in cardiovascular disease: therapeutic challenges and potentials

JD Port, C Sucharov - Journal of cardiovascular pharmacology, 2010 - journals.lww.com
MicroRNAs (miRNAs, miRs) are short approximately 22-nucleotide noncoding RNAs that
bind to messenger RNA transcripts and in doing so modulate cognate gene expression. In …

Clinical applications of miRNAs in cardiac remodeling and heart failure

VK Topkara, DL Mann - Personalized medicine, 2010 - Taylor & Francis
MicroRNAs (miRNAs or miRs) are short, highly conserved noncoding RNAs that regulate
gene expression at the post-transcriptional level by inhibiting translation or promoting the …

Role of microRNAs in cardiac remodeling and heart failure

VK Topkara, DL Mann - Cardiovascular drugs and therapy, 2011 - Springer
MicroRNAs (miRNAs) are endogenous, short (~ 22 nucleotide), evolutionarily conserved,
non-coding RNAs that regulate gene expression at the post-transcriptional level. Recent …

The emerging role of microRNAs in cardiac remodeling and heart failure

V Divakaran, DL Mann - Circulation research, 2008 - Am Heart Assoc
Recent studies have suggested a potentially important role for a family of tiny regulatory
RNAs, known as microRNAs (miRNAs or miRs), in the control of diverse aspects of cardiac …

MicroRNAs and heart failure diagnosis: MiR-acle or MiR-age?

DW Markham, JA Hill - Circulation research, 2010 - Am Heart Assoc
Heart disease is the greatest noninfectious health hazard ever to confront the human race. It
is the leading cause of death in industrialized nations, and, accordingly, it is responsible for …