Hyperosmolarity in the small intestine contributes to postprandial ghrelin suppression
J Overduin, TS Tylee, RS Frayo… - American Journal of …, 2014 - journals.physiology.org
Plasma levels of the orexigenic hormone ghrelin are suppressed by meals with an efficacy
dependent on their macronutrient composition. We hypothesized that heterogeneity in …
dependent on their macronutrient composition. We hypothesized that heterogeneity in …
Hyperosmolar duodenal saline infusion lowers circulating ghrelin and stimulates intestinal hormone release in young men
Context The mechanisms regulating the postprandial suppression of ghrelin secretion
remain unclear, but recent observations in rats indicate that an increase in duodenal …
remain unclear, but recent observations in rats indicate that an increase in duodenal …
Role of the duodenum and macronutrient type in ghrelin regulation
J Overduin, RS Frayo, HJ Grill, JM Kaplan… - …, 2005 - academic.oup.com
The orexigenic hormone ghrelin is implicated in preprandial hunger and meal initiation in
part because circulating levels increase before meals and decrease after food intake. The …
part because circulating levels increase before meals and decrease after food intake. The …
Effect of small intestinal glucose load on plasma ghrelin in healthy men
K Cukier, AN Pilichiewicz… - American Journal …, 2008 - journals.physiology.org
Postprandial ghrelin suppression arises from the interaction of meal contents with the small
intestine and may relate to elevations in blood glucose and/or plasma insulin. We sought to …
intestine and may relate to elevations in blood glucose and/or plasma insulin. We sought to …
Direct effects of nutrients, acetylcholine, CCK, and insulin on ghrelin release from the isolated stomachs of rats
YB Shrestha, K Wickwire, SQ Giraudo - Peptides, 2009 - Elsevier
Ghrelin is a powerful orexigenic peptide predominantly secreted by the stomach. Blood
concentration of ghrelin increases before meals and fall postprandial. Its regulation appears …
concentration of ghrelin increases before meals and fall postprandial. Its regulation appears …
Long-term infusion of nutrients (total parenteral nutrition) suppresses circulating ghrelin in food-deprived rats
SS Qader, A Salehi, R Håkanson, I Lundquist… - Regulatory peptides, 2005 - Elsevier
BACKGROUND: Ghrelin derives from endocrine cells (A-like cells) in the stomach (mainly
the oxyntic mucosa). Its concentration in the circulation increases during fasting and …
the oxyntic mucosa). Its concentration in the circulation increases during fasting and …
Meal-related ghrelin suppression requires postgastric feedback
DL Williams, DE Cummings, HJ Grill… - Endocrinology, 2003 - academic.oup.com
Plasma ghrelin levels are rapidly suppressed by ingestion or gastric delivery of nutrients.
Given that the majority of circulating ghrelin appears to be of gastric origin, we addressed …
Given that the majority of circulating ghrelin appears to be of gastric origin, we addressed …
The effect of ingested macronutrients on postprandial ghrelin response: a critical review of existing literature data
C Koliaki, A Kokkinos, N Tentolouris… - … journal of peptides, 2010 - Wiley Online Library
Ghrelin is a powerful orexigenic gut hormone with growth hormone releasing activity. It plays
a pivotal role for long‐term energy balance and short‐term food intake. It is also recognized …
a pivotal role for long‐term energy balance and short‐term food intake. It is also recognized …
Enhanced gastrointestinal motility with orally active ghrelin receptor agonists
S Charoenthongtrakul, D Giuliana, KA Longo… - … of Pharmacology and …, 2009 - ASPET
The orexigenic peptide ghrelin has been shown to have prokinetic activity in the
gastrointestinal (GI) system of several species, including humans. In this series of …
gastrointestinal (GI) system of several species, including humans. In this series of …
The nutritional control of ghrelin secretion in humans: the effects of enteral vs. parenteral nutrition
F Prodam, E Me, F Riganti, E Gramaglia… - European journal of …, 2006 - Springer
Background The nutritional control of ghrelin has not been fully clarified yet. Particularly, the
influence of aminoacids and lipids is controversial and, moreover, whether the intraluminal …
influence of aminoacids and lipids is controversial and, moreover, whether the intraluminal …